PIPERILATE

US Previously Marketed

First approved in 1959

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H25NO3
Molecular Weight	339.4281
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(C(=O)OCCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=RZWPJFMNFATBEG-UHFFFAOYSA-N

InChI=1S/C21H25NO3/c23-20(25-17-16-22-14-8-3-9-15-22)21(24,18-10-4-1-5-11-18)19-12-6-2-7-13-19/h1-2,4-7,10-13,24H,3,8-9,14-17H2

HIDE SMILES / InChI

Molecular Formula	C21H25NO3
Molecular Weight	339.4281
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/piperilate.html | https://www.drugs.com/international/pipethanate.html | https://www.canada.ca/content/dam/hc-sc/migration/hc-sc/dhp-mps/alt_formats/pdf/prodpharma/pdl-ord/pdl_list_fin_ord-eng.pdf | https://www.kegg.jp/entry/D08384

Piperilate is an antispasmodic, antimuscarinic agent. It is a muscarinic cholinergic receptor antagonist.

Originator

Approval Year

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY555321	https://www.001chemical.com/chem/4546-39-8
ABI Chem	AC1L2GRR
Alfa Chemistry	4546-39-8	https://www.alfa-chemistry.com/cas_4546-39-8.htm
BOC Sciences	4544-15-4
BOC Sciences	4546-39-8
Chemieliva Pharmaceutical Co., Ltd	PBCM1310159
Compound Cloud	20674
Compound Cloud	23724801
Enamine	Z242913010
Lab Network	LN03025710
MolPort	MolPort-047-413-391	https://www.molport.com/shop/molecule-link/MolPort-047-413-391
Molcore	MC555321	https://www.molcore.com/product/4546-39-8
NCI Plated 2007	30793
NovoSeek	20674
Smolecule	S603668	https://www.smolecule.com/products/s603668
THE BioTek	bt-428403	https://www.thebiotek.com/product/others/bt-428403
ZINC	ZINC000000188746	http://zinc15.docking.org/substances/ZINC000000188746
eMolecules	110039667
mcule	MCULE-4466885623
mcule	MCULE-7022732928

PubMed

Title	Date	PubMed
Simple analysis of diphenylmethane antihistaminics and their analogues in bodily fluids by headspace solid-phase microextraction-capillary gas chromatography.	1997 Jun	9172412

Patents

Sample Use Guides

In Vivo Use Guide

mouse LD50 intravenous 38mg/kg (38mg/kg) mouse LD50 oral 510mg/kg (510mg/kg)

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:26:01 GMT 2023` Edited by `admin` on `Fri Dec 15 15:26:01 GMT 2023`
Record UNII	P32MG14U83
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PIPERILATE

Common Name

English

.ALPHA.-HYDROXY-.ALPHA.-PHENYL-, 2-(1-PIPERIDINYL)ETHYL ESTER

Common Name

English

PIPETHANATE

Official Name

English

Pipethanate [WHO-DD]

Common Name

English

pipethanate [INN]

Common Name

English

PIPERILATE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66880