Flezurafenib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H21FN4O3
Molecular Weight	456.4683
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC=C(C=C1)C2=CNC(=N2)[C@H]3COC4=C(C3)C=C(OC5=C6CCC(=O)NC6=NC=C5)C=C4

InChI

InChIKey=TWJSMWXWCWQPRO-QGZVFWFLSA-N

InChI=1S/C26H21FN4O3/c27-18-3-1-15(2-4-18)21-13-29-25(30-21)17-11-16-12-19(5-7-22(16)33-14-17)34-23-9-10-28-26-20(23)6-8-24(32)31-26/h1-5,7,9-10,12-13,17H,6,8,11,14H2,(H,29,30)(H,28,31,32)/t17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C26H21FN4O3
Molecular Weight	456.4683
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 16:15:32 GMT 2025` Edited by `admin` on `Wed Apr 02 16:15:32 GMT 2025`
Record UNII	P26TTM6U27
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

flezurafenib [INN]

Preferred Name

English

Flezurafenib

Official Name

English

1,8-Naphthyridin-2(1H)-one, 5-[[(3S)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-1-benzopyran-6-yl]oxy]-3,4-dihydro-

Systematic Name

English

5-({(3S)-3-[4-(4-fluorophenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-1-benzopyran-6-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one

Systematic Name

English

Code System Code Type Description

INN

12891