4-METHOXYPHENCYCLIDINE

COC1=CC=C(C=C1)C2(CCCCC2)N3CCCCC3

InChIKey=MUZGGFNYVLGUFS-UHFFFAOYSA-N

InChI=1S/C18H27NO/c1-20-17-10-8-16(9-11-17)18(12-4-2-5-13-18)19-14-6-3-7-15-19/h8-11H,2-7,12-15H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Glutamate [NMDA] receptor 125 Target ID: CHEMBL2094124 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23527166	Antagonist 2849	404.0 nM [Ki]
Serotonin transporter 183 Target ID: CHEMBL228 Sources: ncbi.nlm.nih.gov/pubmed/23527166	Binding Agent 1076	844.0 nM [Ki]
Norepinephrine transporter 197 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23527166	Binding Agent 1076	713.0 nM [Ki]
Sigma non-opioid intracellular receptor 1 26 Target ID: Q99720\|\|\|Q7Z653 Gene ID: 10280.0 Gene Symbol: SIGMAR1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/23527166	Binding Agent 1076	296.0 nM [Ki]
Transmembrane protein 97 11 Target ID: Q5BJF2 Gene ID: 27346.0 Gene Symbol: TMEM97 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/23527166	Binding Agent 1076	143.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:21:18 GMT 2025` Edited by `admin` on `Mon Mar 31 23:21:18 GMT 2025`
Record UNII	OZM0C31BLL
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

4-METHOXYPHENCYCLIDINE

Common Name

English

4-MEO-PCP

Preferred Name

English

1-(1-(4-METHOXYPHENYL)CYCLOHEXYL)PIPERIDINE

Systematic Name

English

METHOXYDINE

Common Name

English

PIPERIDINE, 1-(1-(4-METHOXYPHENYL)CYCLOHEXYL)-

Systematic Name

English

N-(1-(4-METHOXYPHENYL)CYCLOHEXYL)PIPERIDINE

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA