GLOXAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H16N6OS2
Molecular Weight	276.382
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of GLOXAZONE

Structure Search

SMILES

CCOC(C)C(C=NNC(N)=S)=NNC(N)=S

InChI

InChIKey=ARIFZLJIERKKEL-UHFFFAOYSA-N

InChI=1S/C8H16N6OS2/c1-3-15-5(2)6(12-14-8(10)17)4-11-13-7(9)16/h4-5H,3H2,1-2H3,(H3,9,13,16)(H3,10,14,17)

HIDE SMILES / InChI

Molecular Formula	C8H16N6OS2
Molecular Weight	276.382
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	2
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6451008

Gloxazone is a drug tested against anaplasmosis and cowdriosis, both tick-borne diseases. It was found to cause toxicity in the kidneys of rats and also had unacceptably high toxic levels in lactating cattle.

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:44:21 GMT 2023` Edited by `admin` on `Fri Dec 15 18:44:21 GMT 2023`
Record UNII	OP8B49OL1J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GLOXAZONE

Official Name

English

CONTRAPAR

Brand Name

English

BW 356-C-61

Code

English

3-Ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone)

Systematic Name

English

gloxazone [INN]

Common Name

English

HYDRAZINECARBOTHIOAMIDE, 2,2'-(1-(1-ETHOXYETHYL)-1,2-ETHANEDIYLIDENE)BIS-

Systematic Name

English

BW-356C61

Code

English

GLOXAZONE [USAN]

Common Name

English

BW-356-C-61

Code

English

NSC-82116

Code

English

(1-ETHOXYETHYL)GLYOXAL BIS(THIOSEMICARBAZONE)

Systematic Name

English

KETHOXAL BIS(THIOSEMICARBAZONE) [MI]

Common Name

English

KETHOXAL BIS(THIOSEMICARBAZONE)

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

Code System Code Type Description

ECHA (EC/EINECS)

219-715-6

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

MERCK INDEX

m6617

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

Merck Index

MESH

C072679

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

CAS

2507-91-7

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

NCI_THESAURUS

C76265

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

ChEMBL

CHEMBL1981146

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

PUBCHEM

6399216

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

SMS_ID

100000084225

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

EPA CompTox

DTXSID70862975

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

INN

2473

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

NSC

82116

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

EVMPD

SUB07934MIG

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

FDA UNII

OP8B49OL1J

Created by admin on Fri Dec 15 18:44:21 GMT 2023 , Edited by admin on Fri Dec 15 18:44:21 GMT 2023

PRIMARY

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					F5TIH1ML7R

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GLOXAZONE, (S)-

ENANTIOMER -> RACEMATE

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					OP8B49OL1J

GLOXAZONE

ACTIVE MOIETY