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Details

Stereochemistry EPIMERIC
Molecular Formula C20H29NO3
Molecular Weight 331.4492
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROPENZOLATE

SMILES

CN1CCC[C@H](C1)OC(=O)C(O)(C2CCCCC2)C3=CC=CC=C3

InChI

InChIKey=LCFBCKSQWVQIBY-QSVWIEALSA-N
InChI=1S/C20H29NO3/c1-21-14-8-13-18(15-21)24-19(22)20(23,16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2,4-5,9-10,17-18,23H,3,6-8,11-15H2,1H3/t18-,20?/m1/s1

HIDE SMILES / InChI

Molecular Formula C20H29NO3
Molecular Weight 331.4492
Charge 0
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 1 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Propenzolate is a pyridine derivative patented by National Research Development Corp. as an anticholinergic agent. Propenzolate is effective antidotes to the cholinesterase-inhibiting action of various organophosphorus compounds. In clinical trials, Propenzolate has an activity that decreases to some extent the secretion of hydrochloric acid and the volume of gastric juice. Adverse effects, including nausea, vomiting, weakness, and drowsiness, as well as xerostomia and cycloplegia, are observed in a high percentage of patients receiving 0.5 to 1.0 mg. every 12 hours.

Approval Year

PubMed

PubMed

TitleDatePubMed
Gastrointestinal motility in man: a study of propenzolate.
1967 Sep
Patents

Patents

Sample Use Guides

0.5 to 1.0 mg. every 12 hours.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:42:19 GMT 2023
Edited
by admin
on Sat Dec 16 16:42:19 GMT 2023
Record UNII
OP853VBF2G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROPENZOLATE
MI  
Common Name English
OXYCLIPINE
INN  
INN  
Official Name English
(+)-1-METHYL-3-PIPERIDYL (±)-.ALPHA.-PHENYLCYCLOHEXANEGLYCOLATE
Systematic Name English
PROPENZOLATE [MI]
Common Name English
BENZENEACETIC ACID, .ALPHA.-CYCLOHEXYL-.ALPHA.-HYDROXY-, (±)-, (+)-1-METHYL-3-PIPERIDINYL ESTER
Common Name English
oxyclipine [INN]
Common Name English
Code System Code Type Description
SMS_ID
100000083301
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
NCI_THESAURUS
C174806
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
EVMPD
SUB09560MIG
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
DRUG CENTRAL
3821
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
INN
1334
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID701017031
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
CAS
4354-45-4
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
FDA UNII
OP853VBF2G
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
MERCK INDEX
m438
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY Merck Index
ChEMBL
CHEMBL2111025
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
PUBCHEM
118984357
Created by admin on Sat Dec 16 16:42:19 GMT 2023 , Edited by admin on Sat Dec 16 16:42:19 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY