7,8-BIS(((METHYLAMINO)CARBONYL)OXY)-2-PHENYL-4H-1-BENZOPYRAN-4-ONE

CNC(=O)OC1=CC=C2C(=O)C=C(OC2=C1OC(=O)NC)C3=CC=CC=C3

InChIKey=NWWRHMSYZTWUBD-UHFFFAOYSA-N

InChI=1S/C19H16N2O6/c1-20-18(23)26-14-9-8-12-13(22)10-15(11-6-4-3-5-7-11)25-16(12)17(14)27-19(24)21-2/h3-10H,1-2H3,(H,20,23)(H,21,24)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
glutathione biosynthetic process 2 Target ID: GO:0006750 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23748647	Activator 1430
reactive oxygen species metabolic process 68 Target ID: GO:0072593 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23748647	Modulator 828
Cytochrome P450 19A1 39 Target ID: CHEMBL1978 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9435150	Inhibitor 8297	10.0 µM [Ki]
Neurotrophic tyrosine kinase receptor type 2 14 Target ID: CHEMBL4898 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20133810	Agonist 2678	320.0 nM [Kd]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:02:42 GMT 2023` Edited by `admin` on `Sat Dec 16 15:02:42 GMT 2023`
Record UNII	OGG19T0LU2
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

7,8-BIS(((METHYLAMINO)CARBONYL)OXY)-2-PHENYL-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

4H-1-BENZOPYRAN-4-ONE, 7,8-BIS(((METHYLAMINO)CARBONYL)OXY)-2-PHENYL-

Systematic Name

English

R13 (DRUG)

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID001336367