7,8-DIHYDROXYFLAVONE

OC1=C(O)C2=C(C=C1)C(=O)C=C(O2)C3=CC=CC=C3

InChIKey=COCYGNDCWFKTMF-UHFFFAOYSA-N

InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
glutathione biosynthetic process 2 Target ID: GO:0006750 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23748647	Activator 1447
reactive oxygen species metabolic process 68 Target ID: GO:0072593 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23748647	Modulator 846
Cytochrome P450 19A1 39 Target ID: CHEMBL1978 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9435150	Inhibitor 8504	10.0 µM [Ki]
Neurotrophic tyrosine kinase receptor type 2 14 Target ID: CHEMBL4898 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20133810	Agonist 2752	320.0 nM [Kd]

Substance Class	Chemical Created by `admin` on `Tue Apr 01 17:00:17 GMT 2025` Edited by `admin` on `Tue Apr 01 17:00:17 GMT 2025`
Record UNII	ADB6MA8ZV2
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

7,8-DIHYDROXYFLAVONE

Systematic Name

English

FEMA NO. 4830

Preferred Name

English

4H-1-BENZOPYRAN-4-ONE, 7,8-DIHYDROXY-2-PHENYL-

Systematic Name

English

NSC-750341

Code

English

7,8-DHF

Common Name

English

7,8-DIHYDROXY-2-PHENYL-4H-1-BENZOPYRAN-4-ONE

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

253-812-4