DIFEMETOREX

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H25NO
Molecular Weight	295.4186
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCN1CCCCC1C(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=UHZJPVXMMCFPNR-UHFFFAOYSA-N

InChI=1S/C20H25NO/c22-16-15-21-14-8-7-13-19(21)20(17-9-3-1-4-10-17)18-11-5-2-6-12-18/h1-6,9-12,19-20,22H,7-8,13-16H2

HIDE SMILES / InChI

Molecular Formula	C20H25NO
Molecular Weight	295.4186
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://medkoo.com/products/20049 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 452, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://www.ncbi.nlm.nih.gov/pubmed/5089225 | https://www.ncbi.nlm.nih.gov/pubmed/5072180

Difemetorex is a stimulant drug of the piperidine class. It was used as an appetite suppressant, anorectic agent. Difemetorex has intolerable side effects such as insomnia, which limited its clinical use.

Approval Year

PubMed

Title	Date	PubMed
[Alteration of the acid-base equilibrium by the anorectic diphemethoxidine in comparison with the effect of amphetamine and aminorex].	1972-09	5072180
[Circulatory effects of the anorectic Diphemethoxidine compared with the effects of Amphetamine and Aminorex].	1971-06	5089225

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:27:24 GMT 2025` Edited by `admin` on `Mon Mar 31 18:27:24 GMT 2025`
Record UNII	O0417MPF6W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIFEMETOREX

Official Name

English

BA-28289

Preferred Name

English

DIPHEMETHOXIDINE [MI]

Common Name

English

2-(DIPHENYLMETHYL)-1-PIPERIDINEETHANOL

Systematic Name

English

difemetorex [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29728