TEPRASIRAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 09:44:31 GMT 2023` Edited by `admin` on `Sat Dec 16 09:44:31 GMT 2023`
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	O03W5S19PJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TEPRASIRAN

Official Name

English

RNA, (G-AM-G-AM-A-UM-A-UM-U-UM-C-AM-C-CM-C-UM-U-CM-A), COMPLEX WITH RNA (UM-G-AM-A-GM-G-GM-U-GM-A-AM-A-UM-A-UM-U-CM-U-CM) (1:1)

Systematic Name

English

I5-NP

Code

English

QPI-1002

Code

English

Teprasiran [WHO-DD]

Common Name

English

TEPRASIRAN [USAN]

Common Name

English

GUANYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-GUANYLYL- (3'->5')-2'-O-METHYLADENYLYL-(3'->5')-ADENYLYL-(3'->5')-2'-OMETHYLURIDYLYL-(3'->5')-ADENYLYL-(3'->5')-2'-O-METHYLURIDYLYL- (3'->5')-URIDYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')- CYTIDYLYL-(3'->5'

Systematic Name

English

I5NP

Code

English

teprasiran [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

296509

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

NCI_THESAURUS

C78274

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C152565

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

PRIMARY

CAS

1231737-88-4

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

PRIMARY

USAN

FG-142

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

PRIMARY

DRUG BANK

DB15064

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

PRIMARY

INN

10513

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

PRIMARY

FDA UNII

O03W5S19PJ

Created by admin on Sat Dec 16 09:44:31 GMT 2023 , Edited by admin on Sat Dec 16 09:44:31 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_2;1_4;1_6;1_8;1_10;1_12;1_14;1_16;1_18;2_1;2_3;2_5;2_7;2_9;2_11;2_13;2_15;2_17;2_19	19 / 38
2'-O-Methyl-Ribose	1_1;1_3;1_5;1_7;1_9;1_11;1_13;1_15;1_17;1_19;2_2;2_4;2_6;2_8;2_10;2_12;2_14;2_16;2_18	19 / 38

Linkage	Site Range	Site Count
Phosphate	1_2-1_19;2_2-2_19	36 / 36

Related Record Type Details


					ME0IRL7KDY

TEPRASIRAN SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					O03W5S19PJ

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL