| Stereochemistry | ABSOLUTE |
| Molecular Formula | C25H40O2S |
| Molecular Weight | 404.649 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 9 / 9 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@H](OC3(CCCC3)OC)[C@@]1(C)CC[C@@]4([H])[C@@]2([H])CC[C@@]5([H])C[C@@H]6S[C@@H]6C[C@]45C
InChI
InChIKey=IVDYZAAPOLNZKG-KWHRADDSSA-N
InChI=1S/C25H40O2S/c1-23-13-10-19-17(7-6-16-14-20-21(28-20)15-24(16,19)2)18(23)8-9-22(23)27-25(26-3)11-4-5-12-25/h16-22H,4-15H2,1-3H3/t16-,17-,18-,19-,20-,21+,22-,23-,24-/m0/s1
| Molecular Formula | C25H40O2S |
| Molecular Weight | 404.649 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 9 / 9 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Mepitiostane is a epitiostanol prodrug that was developed in Japan by Shionogi. The drug is approved and used exclusively in Japan for the treatment of breast carcinoma and anemia associated with renal failure. Upon administration mepitiostane is metabolized to the active metabolite which binds to and inhibits estrogen receptors.
