U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 14:36:00 GMT 2023
Edited
by admin
on Sat Dec 16 14:36:00 GMT 2023
Source Materials Class ORGANISM
Source Materials Type BACTERIUM
Source Materials State LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family Listeriaceae
Organism Genus Listeria
Organism Species monocytogenes
Author (MURRAY ET AL., 1926) PIRIE, 1940
Infraspecific Type STRAIN
Infraspecific Name XFL-7
Part WHOLE
Record UNII
NY7PTD1862
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AXALIMOGENE FILOLISBAC
INN  
Official Name English
axalimogene filolisbac [INN]
Common Name English
Axalimogene filolisbac [WHO-DD]
Common Name English
ADXS11-001
Code English
LIVE, ATTENUATED LISTERIA MONOCYTOGENES BACTERIA, EXPRESSING HUMAN PAPILLOMA VIRUS TYPE 16-E7 TUMOR ANTIGEN
Common Name English
RALIGIZE
Common Name English
ADXS HPV
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 401813
Created by admin on Sat Dec 16 14:36:00 GMT 2023 , Edited by admin on Sat Dec 16 14:36:00 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C74595
Created by admin on Sat Dec 16 14:36:00 GMT 2023 , Edited by admin on Sat Dec 16 14:36:00 GMT 2023
PRIMARY
INN
10039
Created by admin on Sat Dec 16 14:36:00 GMT 2023 , Edited by admin on Sat Dec 16 14:36:00 GMT 2023
PRIMARY
FDA UNII
NY7PTD1862
Created by admin on Sat Dec 16 14:36:00 GMT 2023 , Edited by admin on Sat Dec 16 14:36:00 GMT 2023
PRIMARY
Related Record Type Details
TARGET->ANTIGEN
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
TRANSFECTION PLASMID TRANSFECTION UNSPECIFIED SUBSTANCE 930be0ae

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
VECTOR EXPRESSED PROTEIN EXCRETED LISTERIOLYSIN O TRUNCATED AND FUSED TO THE HUMAN PAPILLOMA VIRUS-16 (HPV-16) E7 PROTEIN A6PQS1J3Q0