NORAMIDOPYRINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H15N3O
Molecular Weight	217.267
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC1=C(C)N(C)N(C1=O)C2=CC=CC=C2

InChI

InChIKey=JILCEWWZTBBOFS-UHFFFAOYSA-N

InChI=1S/C12H15N3O/c1-9-11(13-2)12(16)15(14(9)3)10-7-5-4-6-8-10/h4-8,13H,1-3H3

HIDE SMILES / InChI

Molecular Formula	C12H15N3O
Molecular Weight	217.267
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Population pharmacokinetic analysis of the active product of dipyrone.	2010-12	21084034
Investigation of the microbial degradation of phenazone-type drugs and their metabolites by natural biofilms derived from river water using liquid chromatography/tandem mass spectrometry (LC-MS/MS).	2010-08	20619430
Scavenging activity of aminoantipyrines against hydroxyl radical.	2010-06	20172632
Quantification of 4-methylaminoantipyrine, the active metabolite of dipyrone, in human plasma.	2009-05	21083168
Treatment of postherpetic neuralgia: focus on pregabalin.	2009	19503762
Photodegradation study of three dipyrone metabolites in various water systems: identification and toxicity of their photodegradation products.	2008-05	18294672
Pyrazolinone analgesics prevent the antiplatelet effect of aspirin and preserve human platelet thromboxane synthesis.	2008-01	17944992
Clinical review: Drug metabolism and nonrenal clearance in acute kidney injury.	2008	19040780
[Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography].	2007-11	18257301
[Favorable outcome of acute porphyric neuropathy after treatment with heme arginate].	2007-11	18033050
Dipyrone elicits substantial inhibition of peripheral cyclooxygenases in humans: new insights into the pharmacology of an old analgesic.	2007-08	17435173
Solid-phase extraction followed by liquid chromatography-time-of-flight-mass spectrometry to evaluate pharmaceuticals in effluents. A pilot monitoring study.	2007-07	17607393
Inhibition of cyclooxygenases by dipyrone.	2007-06	17435797
[Drug-induced agranulocytosis in rheumatology. A retrospective study of 12 cases].	2007-04-23	17627927
Simultaneous determination of residues of dipyrone and its major metabolites in milk, bovine muscle, and porcine muscle by liquid chromatography/mass spectrometry.	2005-04-30	15859077
Characterization of the role of physicochemical factors on the hydrolysis of dipyrone.	2004-05-28	15137974
Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells. Comparative analysis with acetylsalicylic acid and diclofenac.	2003-01-15	12504796
Allergic cholestatic hepatitis and exanthema induced by metamizole: verification by lymphocyte transformation test.	2002-12	12445177
Bioavailability of two metamizole (dipyrone) solutions as single doses of 2 g versus metamizole capsules.	2002-07	12139210
Benzydamine: an alternative nonsteroidal anti-inflammatory drug in patients with nimesulide-induced urticaria.	2002-05	11972485
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.	2001-11	11792017
Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone.	2001-11	11668360
Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis-B virus does not occur in rapid acetylators.	2001-09	11699610
Acute hepatitis due to ketoprofen.	1991-06	1914425

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:52:12 GMT 2025` Edited by `admin` on `Mon Mar 31 18:52:12 GMT 2025`
Record UNII	NER31DE951
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NORAMIDOPYRINE

Common Name

English

NORAMINOPYRINE

Preferred Name

English

1,5-DIMETHYL-4-METHYLAMINO-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE

Systematic Name

English

Noramidopyrine [WHO-DD]

Common Name

English

N-METHYL-4-AMINOPHENAZONE

Systematic Name

English

N-METHYLAMINOPHENAZONE

Systematic Name

English

4-Methylaminoantipyrine

Common Name

English

METAMIZOLE SODIUM MONOHYDRATE IMPURITY C [EP IMPURITY]

Common Name

English

Code System Code Type Description

CAS

519-98-2