U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H18N4O3
Molecular Weight 278.307
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LOMIFYLLINE

SMILES

CN1C2=C(N(CCCCC(C)=O)C=N2)C(=O)N(C)C1=O

InChI

InChIKey=XBEDAMVJWVPVDS-UHFFFAOYSA-N
InChI=1S/C13H18N4O3/c1-9(18)6-4-5-7-17-8-14-11-10(17)12(19)16(3)13(20)15(11)2/h8H,4-7H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C13H18N4O3
Molecular Weight 278.307
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Lomifylline is a xanthine derivative with peripheral vasodilator action. Lomifylline in combination with dihydroergocristine (CERVILANE) is used in the treatment of vertigo of vascular origin.

Approval Year

Patents

Patents

Sample Use Guides

CERVILANE (Lomifylline 80 mg, dihydroergocristine mesylate 0.8 mg) 3 times daily
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:31:36 GMT 2023
Edited
by admin
on Fri Dec 15 15:31:36 GMT 2023
Record UNII
NA91GV8GDJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LOMIFYLLINE
INN   MART.   WHO-DD  
INN  
Official Name English
lomifylline [INN]
Common Name English
7-(5-OXOHEXYL)THEOPHYLLINE
Systematic Name English
LOMIFYLLINE [MART.]
Common Name English
Lomifylline [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C319
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
NCI_THESAURUS C744
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
Code System Code Type Description
DRUG CENTRAL
3983
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
SMS_ID
100000082004
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
CAS
10226-54-7
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
ECHA (EC/EINECS)
233-547-0
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
MESH
C031576
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
INN
4220
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
EPA CompTox
DTXSID10144848
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
FDA UNII
NA91GV8GDJ
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
NCI_THESAURUS
C66030
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
RXCUI
164423
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY RxNorm
PUBCHEM
65599
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
ChEMBL
CHEMBL311948
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
EVMPD
SUB08566MIG
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY