U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C24H32N2O5
Molecular Weight 428.5213
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FALIPAMIL

SMILES

COC1=CC2=C(C=C1OC)C(=O)N(CCCN(C)CCC3=CC(OC)=C(OC)C=C3)C2

InChI

InChIKey=UUMGNNQOCVDZDG-UHFFFAOYSA-N
InChI=1S/C24H32N2O5/c1-25(12-9-17-7-8-20(28-2)21(13-17)29-3)10-6-11-26-16-18-14-22(30-4)23(31-5)15-19(18)24(26)27/h7-8,13-15H,6,9-12,16H2,1-5H3

HIDE SMILES / InChI

Molecular Formula C24H32N2O5
Molecular Weight 428.5213
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Falipamil (AQ-A 39), a bradycardiac agent is a calcium channel antagonist. Falipamil can be used to normalize sinus rate in patients with sinus tachycardia of various origin, particularly in intensive care, in acute ischemic heart disease, in anesthesia, and in surgery cases. Falipamil development has been discontinued.

Originator

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
1.5-2 mg/kg
Route of Administration: Intravenous
Substance Class Chemical
Record UNII
N6A93ZMN7U
Record Status Validated (UNII)
Record Version