PARBENDAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H17N3O2
Molecular Weight	247.293
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC1=CC2=C(C=C1)N=C(NC(=O)OC)N2

InChI

InChIKey=YRWLZFXJFBZBEY-UHFFFAOYSA-N

InChI=1S/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C13H17N3O2
Molecular Weight	247.293
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7031071 | https://www.ncbi.nlm.nih.gov/pubmed/5812439

Parbendazole is a potent inhibitor of microtubule assembly that was studied as an anthelmintic agent. Information about the current use of this drug is not available.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
microtubule polymerization 21 Target ID: GO:0046785 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6895648	Inhibitor 8504

PubMed

Title	Date	PubMed
Parbendazole.	2010	22469223
Epidemiological aspects of the first outbreak of Baylisascaris procyonis larva migrans in rabbits in Japan.	2003-04	12736426
In vitro susceptibilities of the AIDS-associated microsporidian Encephalitozoon intestinalis to albendazole, its sulfoxide metabolite, and 12 additional benzimidazole derivatives.	1997-12	9420047
Activity of benzimidazoles against cryptosporidiosis in neonatal BALB/c mice.	1995-10	7472880
In vitro susceptibility of the opportunistic fungus Cryptococcus neoformans to anthelmintic benzimidazoles.	1994-02	8192471

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:55:13 GMT 2025` Edited by `admin` on `Mon Mar 31 17:55:13 GMT 2025`
Record UNII	N4X8WVX2UG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-256420

Preferred Name

English

PARBENDAZOLE

Official Name

English

SK&F-29044

Code

English

SK&F 29044

Code

English

PARBENDAZOLE [USP-RS]

Common Name

English

TCMDC-131798

Code

English

PARBENDAZOLE [USAN]

Common Name

English

CARBAMIC ACID, (5-BUTYL-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER

Common Name

English

PARBENDAZOLE [MI]

Common Name

English

parbendazole [INN]

Common Name

English

Methyl 5-butyl-2-benzimidazolecarbamate

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250