TABERSONINE

CC[C@@]12CC(C(=O)OC)=C3NC4=CC=CC=C4[C@@]35CCN(CC=C1)[C@@H]25

InChIKey=FNGGIPWAZSFKCN-ACRUOGEOSA-N

InChI=1S/C21H24N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-9,19,22H,3,10-13H2,1-2H3/t19-,20-,21-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
amyloid fibril formation 8 Target ID: GO:1990000 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25874995	Inhibitor 8504

PubMed

Title	Date	PubMed
Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination.	2018-08	29746822
Tabersonine inhibits amyloid fibril formation and cytotoxicity of Aβ(1-42).	2015-06-17	25874995
A Cytochrome P-450 Monooxygenase Catalyzes the First Step in the Conversion of Tabersonine to Vindoline in Catharanthus roseus.	1995-09	12228585

Substance Class	Chemical Created by `admin` on `Tue Apr 01 19:27:47 GMT 2025` Edited by `admin` on `Tue Apr 01 19:27:47 GMT 2025`
Record UNII	MN955K48NB
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

TABERSONINE

Common Name

English

(-)-TABERSONINE

Preferred Name

English

TABERSONIN

Common Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, (5.ALPHA.,12R,19.ALPHA.)-

Systematic Name

English

1H-INDOLIZINO(8,1-CD)CARBAZOLE-5-CARBOXYLIC ACID, 3A-ETHYL-3A,4,6,11,12,13A-HEXAHYDRO-, METHYL ESTER

Common Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, (5.ALPHA.,12.BETA.,19.ALPHA.)-

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

224-615-0