TABERSONINE HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H24N2O2.ClH
Molecular Weight	372.888
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC[C@@]12CC(C(=O)OC)=C3NC4=CC=CC=C4[C@@]35CCN(CC=C1)[C@@H]25

InChI

InChIKey=BBASQSWPQOKOQI-OCIDDWSYSA-N

InChI=1S/C21H24N2O2.ClH/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2;/h4-9,19,22H,3,10-13H2,1-2H3;1H/t19-,20-,21-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C21H24N2O2
Molecular Weight	336.4275
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
amyloid fibril formation 8 Target ID: GO:1990000 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25874995	Inhibitor 8504

PubMed

Title	Date	PubMed
Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination.	2018-08	29746822
Tabersonine inhibits amyloid fibril formation and cytotoxicity of Aβ(1-42).	2015-06-17	25874995
A Cytochrome P-450 Monooxygenase Catalyzes the First Step in the Conversion of Tabersonine to Vindoline in Catharanthus roseus.	1995-09	12228585

Substance Class	Chemical Created by `admin` on `Wed Apr 02 13:39:58 GMT 2025` Edited by `admin` on `Wed Apr 02 13:39:58 GMT 2025`
Record UNII	DGR7D6J5TR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TABERSONINE MONOHYDROCHLORIDE

Preferred Name

English

TABERSONINE HYDROCHLORIDE

Common Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, HYDROCHLORIDE (1:1), (5.ALPHA.,12R,19.ALPHA.)-

Systematic Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, MONOHYDROCHLORIDE, (5.ALPHA.,12R,19.ALPHA.)-

Systematic Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, MONOHYDROCHLORIDE, (5.ALPHA.,12.BETA.,19.ALPHA.)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

12443187

Created by admin on Wed Apr 02 13:39:58 GMT 2025 , Edited by admin on Wed Apr 02 13:39:58 GMT 2025

PRIMARY

FDA UNII

DGR7D6J5TR

Created by admin on Wed Apr 02 13:39:58 GMT 2025 , Edited by admin on Wed Apr 02 13:39:58 GMT 2025

PRIMARY

CAS

29479-00-3

Created by admin on Wed Apr 02 13:39:58 GMT 2025 , Edited by admin on Wed Apr 02 13:39:58 GMT 2025

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TABERSONINE

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Amount: