TABERSONINE HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H24N2O2.ClH
Molecular Weight	372.888
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[H][C@@]12N3CC[C@]14C(NC5=C4C=CC=C5)=C(C[C@]2(CC)C=CC3)C(=O)OC

InChI

InChIKey=BBASQSWPQOKOQI-OCIDDWSYSA-N

InChI=1S/C21H24N2O2.ClH/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2;/h4-9,19,22H,3,10-13H2,1-2H3;1H/t19-,20-,21-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C21H24N2O2
Molecular Weight	336.4275
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
amyloid fibril formation 7 Target ID: GO:1990000 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25874995	Inhibitor 8297

PubMed

Title	Date	PubMed
Tabersonine inhibits amyloid fibril formation and cytotoxicity of Aβ(1-42).	2015 Jun 17	25874995
Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination.	2018 Aug	29746822

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:07:10 GMT 2023` Edited by `admin` on `Sat Dec 16 19:07:10 GMT 2023`
Record UNII	DGR7D6J5TR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TABERSONINE HYDROCHLORIDE

Common Name

English

TABERSONINE MONOHYDROCHLORIDE

Common Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, HYDROCHLORIDE (1:1), (5.ALPHA.,12R,19.ALPHA.)-

Systematic Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, MONOHYDROCHLORIDE, (5.ALPHA.,12R,19.ALPHA.)-

Systematic Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-, METHYL ESTER, MONOHYDROCHLORIDE, (5.ALPHA.,12.BETA.,19.ALPHA.)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

12443187

Created by admin on Sat Dec 16 19:07:10 GMT 2023 , Edited by admin on Sat Dec 16 19:07:10 GMT 2023

PRIMARY

FDA UNII

DGR7D6J5TR

Created by admin on Sat Dec 16 19:07:10 GMT 2023 , Edited by admin on Sat Dec 16 19:07:10 GMT 2023

PRIMARY

CAS

29479-00-3

Created by admin on Sat Dec 16 19:07:10 GMT 2023 , Edited by admin on Sat Dec 16 19:07:10 GMT 2023

PRIMARY

Related Record Type Details


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TABERSONINE

PARENT -> SALT/SOLVATE

Amount: