NICAMETATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H18N2O2
Molecular Weight	222.2835
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCOC(=O)C1=CN=CC=C1

InChI

InChIKey=JVWOCHRRAWHKLT-UHFFFAOYSA-N

InChI=1S/C12H18N2O2/c1-3-14(4-2)8-9-16-12(15)11-6-5-7-13-10-11/h5-7,10H,3-4,8-9H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C12H18N2O2
Molecular Weight	222.2835
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.yusheng.com.tw/english/ysc002_Circulatory.html
Curator's Comment: Description was created based on several sources, including https://books.google.ru/books?id=tsjrCAAAQBAJ&pg=PA197&lpg=PA197&dq=NICAMETATE+Vasodilator&source=bl&ots=R3SvlIMrz9&sig=fjPfKUUS4rtrYtdKqukxERpMUBE&hl=en&sa=X&ved=0ahUKEwiWzsuTz-nOAhUGJpoKHdq9AOkQ6AEINjAF#v=onepage&q=NICAMETATE%20Vasodilator&f=false (retrieved from Concise Dictionary of Pharmacological Agents: Properties and Synonyms By I.K. Morton, Judith M. Hall, p.197

Nicametate is a vasodilator, which enhances blood flow and oxygen to the brain, aids stroke recovery. It also can use for treating intermittent claudication in certain patients.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
cell growth 21 Target ID: GO:0016049 Sources: http://www.ncbi.nlm.nih.gov/pubmed/9700242	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Vascular pathology 2 Sources: http://www.ncbi.nlm.nih.gov/pubmed/5079565	Primary		Preclinical	Unknown Approved Use Unknown
Cardiovascular diseases 71 Sources: http://www.ncbi.nlm.nih.gov/pubmed/4211730	Primary		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

300 mg of nicametate citrate daily

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:05:07 GMT 2023` Edited by `admin` on `Sat Dec 16 16:05:07 GMT 2023`
Record UNII	ML4O3WYO2M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NICAMETATE

Official Name

English

NICAMETATE [MI]

Common Name

English

nicametate [INN]

Common Name

English

Nicametate [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707