U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C24H25N7O5
Molecular Weight 491.4992
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Emavusertib

SMILES

CC1=CC(=CC=N1)C2=NC(=CO2)C(=O)NC3=C(N=C4N=C(OC4=C3)N5CCOCC5)N6CC[C@@H](O)C6

InChI

InChIKey=SJHNWSAWWOAWJH-MRXNPFEDSA-N
InChI=1S/C24H25N7O5/c1-14-10-15(2-4-25-14)23-27-18(13-35-23)22(33)26-17-11-19-20(28-21(17)31-5-3-16(32)12-31)29-24(36-19)30-6-8-34-9-7-30/h2,4,10-11,13,16,32H,3,5-9,12H2,1H3,(H,26,33)/t16-/m1/s1

HIDE SMILES / InChI

Molecular Formula C24H25N7O5
Molecular Weight 491.4992
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 13:31:57 GMT 2023
Edited
by admin
on Sat Dec 16 13:31:57 GMT 2023
Record UNII
MH5DMF9JKY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Emavusertib
INN   USAN  
Official Name English
emavusertib [INN]
Common Name English
EMAVUSERTIB [USAN]
Common Name English
N-{5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-(morpholin-4-yl)[1,3]oxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide
Systematic Name English
4-oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-
Systematic Name English
CA-4948
Code English
AU-4948
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 810321
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
FDA ORPHAN DRUG 810221
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
Code System Code Type Description
CAS
1801344-14-8
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
SMS_ID
300000017399
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
USAN
KL-121
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
FDA UNII
MH5DMF9JKY
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
INN
11558
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY INN
EPA CompTox
DTXSID001103300
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
PUBCHEM
118224491
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
NCI_THESAURUS
C148455
Created by admin on Sat Dec 16 13:31:57 GMT 2023 , Edited by admin on Sat Dec 16 13:31:57 GMT 2023
PRIMARY
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