HYDROXYPHENAMATE

First approved in 1961

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H15NO3
Molecular Weight	209.2417
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(O)(COC(N)=O)C1=CC=CC=C1

InChI

InChIKey=WAFIYOULDIWAKR-UHFFFAOYSA-N

InChI=1S/C11H15NO3/c1-2-11(14,8-15-10(12)13)9-6-4-3-5-7-9/h3-7,14H,2,8H2,1H3,(H2,12,13)

HIDE SMILES / InChI

Molecular Formula	C11H15NO3
Molecular Weight	209.2417
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://doi.org/10.1016/S0025-7125(16)33476-9 |

HYDROXYPHENAMATE (LISTICA®) is a carbamate tranquilizer indicated for anxiety. It resembles meprobamate in its effect.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Anxiety 267 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13707512	Primary		Approved 8429	Listica Approved Use Treatment of anxiety and tension. Launch Date 1960

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY556872	https://www.001chemical.com/chem/50-19-1
BLD Pharm	BD146554	http://www.bldpharm.com/products/50-19-1.html
CSNpharm	CSN21779	https://www.csnpharm.com/products/oxyfenamate.html
Chem Scene	CS-6618	http://www.chemscene.com/50-19-1.html
ChemMol	99097705	http://www.chemmol.com/chemmol/99097705.html
LGC Standards	LGCFOR3109.00	https://www.lgcstandards.com/US/en/p/LGCFOR3109.00
LGC Standards	MM3109.00	https://www.lgcstandards.com/US/en/p/MM3109.00
MedChem Express	HY-101754	https://www.medchemexpress.com/Oxyfenamate.html
Molcore	MC556872	https://www.molcore.com/product/50-19-1
Smolecule	S530224	http://www.smolecule.com/products/s530224
THE BioTek	bt-271329	https://www.thebiotek.com/product/inhibitors/bt-271329

PubMed

Title	Date	PubMed
Pharmacology and toxicology of hydroxphenamate (Listica).	1961 Sep	13687675
Amelioration of allergic symptoms with a new tranquilizing drug (Listica).	1961 Sep	13726170
A report on the apparent anticonvulsant effect of hydroxyphenamate (Listica).	1962 Sep	13858828

Patents

Sample Use Guides

In Vivo Use Guide

600 to 800 mg orally.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:00 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:00 GMT 2023`
Record UNII	MD0414799X
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HYDROXYPHENAMATE

Official Name

English

CARBAMIC ACID, .BETA.-ETHYL-.BETA.-HYDROXYPHENETHYL ESTER

Systematic Name

English

HYDROXYPHENAMATE [USAN]

Common Name

English

OXYFENAMATE

Official Name

English

LISTICA

Brand Name

English

P-301

Code

English

2-HYDROXY-2-PHENYLBUTYL CARBAMATE

Systematic Name

English

Oxyfenamate [WHO-DD]

Common Name

English

1,2-BUTANEDIOL, 2-PHENYL-, 1-CARBAMATE

Systematic Name

English

2-Phenyl-1,2-butanediol 1-carbamate

Systematic Name

English

HYDROXYPHENAMATE [MI]

Common Name

English

oxyfenamate [INN]

Common Name

English

AL-0361

Code

English

NSC-108034

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29710