Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C26H36O5 |
| Molecular Weight | 428.561 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@@]3(CCC(=O)O3)[C@@]1(C)CC[C@@]4([H])[C@@]2([H])[C@@H](CC5=CC(=O)CC[C@]45C)C(=O)OC(C)C
InChI
InChIKey=WUVPAYPBMZMHJO-IMNLCBETSA-N
InChI=1S/C26H36O5/c1-15(2)30-23(29)18-14-16-13-17(27)5-9-24(16,3)19-6-10-25(4)20(22(18)19)7-11-26(25)12-8-21(28)31-26/h13,15,18-20,22H,5-12,14H2,1-4H3/t18-,19+,20+,22-,24+,25+,26-/m1/s1
| Molecular Formula | C26H36O5 |
| Molecular Weight | 428.561 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 6 / 7 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Dicirenone is an aldosterone antagonist. It is used as a hypotensive agent. Dicirenone inhibited the effects of aldosterone on urinary K(+):Na(+) ratios and the binding of [(3)H]aldosterone to renal cytoplasmic and nuclear receptors. Dicirenone blocked the action of aldosterone on Na-K ATPase. Cytoplasmic binding of [(3)H]aldosterone and dicirenone was similar in magnitude and involved the same set of sites. It had no effect on adrenal steroidogenesis.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:08:40 GMT 2023
by
admin
on
Fri Dec 15 16:08:40 GMT 2023
|
| Record UNII |
M8K306YKSX
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
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Official Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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Dicirenone
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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10387872
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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M8K306YKSX
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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CHEMBL2106258
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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DTXSID101023456
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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C174699
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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U-2
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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5449
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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SUB07090MIG
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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41020-79-5
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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100000082916
Created by
admin on Fri Dec 15 16:08:40 GMT 2023 , Edited by admin on Fri Dec 15 16:08:40 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
