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Details

Stereochemistry UNKNOWN
Molecular Formula C21H24ClNO
Molecular Weight 341.874
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOBENZTROPINE

SMILES

CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=C(Cl)C=C4

InChI

InChIKey=OCAXFDULERPAJM-UHFFFAOYSA-N
InChI=1S/C21H24ClNO/c1-23-18-11-12-19(23)14-20(13-18)24-21(15-5-3-2-4-6-15)16-7-9-17(22)10-8-16/h2-10,18-21H,11-14H2,1H3

HIDE SMILES / InChI
Molecular Formula C21H24ClNO
Molecular Weight 341.874
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

3-CPMT (3α-[(4-Chlorophenyl)phenylmethoxy] tropane) is a dopamine uptake inhibitor. Behavioral studies suggested that it did not display a cocaine-like behavioral profile, despite their ability to inhibit dopamine uptake.

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
Dopamine transporter
183
Inhibitor
8,504
 30.0 nM [Ki]
Dopamine transporter
183
Inhibitor
8,504
 30.0 nM [Ki]

PubMed

Patents

20110028564
2
20110118136
3
Substance Class Chemical
Record UNII
M8CDT278F8
Record Status Validated (UNII)
Record Version
NIH
NCATS
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