Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C7H15N3O2S |
| Molecular Weight | 205.278 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CSC(=N)NCCC[C@H](N)C(O)=O
InChI
InChIKey=NGVMVBQRKZPFLB-YFKPBYRVSA-N
InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1
| Molecular Formula | C7H15N3O2S |
| Molecular Weight | 205.278 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Renal nitric oxide production in rat pregnancy: role of constitutive nitric oxide synthases. | 2010-10 |
|
| The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney. | 2010-07 |
|
| Expression of neuronal nitric oxide synthase in rabbit carotid body glomus cells regulates large-conductance Ca2+-activated potassium currents. | 2010-06 |
|
| Oxytocin induces penile erection when injected into the ventral subiculum: role of nitric oxide and glutamic acid. | 2010-06 |
|
| Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice. | 2010-05 |
|
| Chemical modulators of the innate immune response alter gypsy moth larval susceptibility to Bacillus thuringiensis. | 2010-04-27 |
|
| Effects of neuronal nitric oxide synthase inhibition on resting and exercising hindlimb muscle blood flow in the rat. | 2010-04-15 |
|
| Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney. | 2010-02 |
|
| Contribution of neuronal nitric oxide (no) synthase to N-acetylcysteine-induced increase of NO synthase activity in the brain of normotensive and hypertensive rats. | 2009-12 |
|
| Neuronal nitric oxide synthase and human vascular regulation. | 2009-11 |
|
| Long-term ventilatory adaptation and ventilatory response to hypoxia in plateau pika (Ochotona curzoniae): role of nNOS and dopamine. | 2009-10 |
|
| Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure. | 2009-07 |
|
| Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo. | 2009-05-26 |
|
| A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice. | 2009-02 |
|
| Exercise training improves peripheral chemoreflex function in heart failure rabbits. | 2008-09 |
|
| Oxytocin induces penile erection when injected into the ventral tegmental area of male rats: role of nitric oxide and cyclic GMP. | 2008-08 |
|
| Altered mesenteric venous capacitance and volume pooling in cirrhotic rats are mediated by nitric oxide. | 2008-08 |
|
| Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase. | 2008-07 |
|
| Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. II. Effects of renal mass reduction. | 2008-06 |
|
| Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban. | 2008-06 |
|
| Non-invasive measurements of exhaled NO and CO associated with methacholine responses in mice. | 2008-05-27 |
|
| Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo. | 2008-04-15 |
|
| Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats. | 2008-04 |
|
| Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress. | 2008-02 |
|
| Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension. | 2008-01 |
|
| Brain stem NO modulates ventilatory acclimatization to hypoxia in mice. | 2007-11 |
|
| A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine. | 2007-11 |
|
| Does nitric oxide act in the ventromedial preoptic area to mediate oestrogen negative feedback in the seasonally anoestrous ewe? | 2007-07 |
|
| [Effects of new nitric oxide synthase inhibitors on spontaneous locomotor activity]. | 2007-03-10 |
|
| Coordination of kidney filtration and tubular reabsorption: considerations on the regulation of metabolic demand for tubular reabsorption. | 2007-03 |
|
| Renal tissue NO and intrarenal haemodynamics during experimental variations of NO content in anaesthetised rats. | 2007-03 |
|
| nNOS is involved in behavioral thermoregulation of newborn rats during hypoxia. | 2006-12-30 |
|
| PIP3EA and PD-168077, two selective dopamine D4 receptor agonists, induce penile erection in male rats: site and mechanism of action in the brain. | 2006-10 |
|
| Endothelin-1 stimulates NO production and inhibits cAMP accumulation in rat inner medullary collecting duct through independent pathways. | 2006-06 |
|
| Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa. | 2006-05-02 |
|
| Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. | 2006-04 |
|
| The cannabinoid receptor antagonist SR-141716A induces penile erection in male rats: involvement of paraventricular glutamic acid and nitric oxide. | 2006-02 |
|
| Nitric oxide inhibition and the impact on renal nerve-mediated antinatriuresis and antidiuresis in the anaesthetized rat. | 2005-12-15 |
|
| Nitric oxide synthase inhibition affects sarcoplasmic reticulum Ca2+ release in skeletal muscle fibres from mouse. | 2005-09-15 |
|
| A continuous spectrophotometric assay for dimethylarginine dimethylaminohydrolase. | 2005-08-15 |
|
| Gene transfer of neuronal nitric oxide synthase to carotid body reverses enhanced chemoreceptor function in heart failure rabbits. | 2005-08-05 |
|
| Nitric oxide and cGMP mediate alpha1D-adrenergic receptor-Stimulated protein secretion and p42/p44 MAPK activation in rat lacrimal gland. | 2005-08 |
|
| Oxygen consumption in the kidney: effects of nitric oxide synthase isoforms and angiotensin II. | 2005-08 |
|
| Hypothalamic release of nitric oxide and interaction with amino acid neurotransmitters in chronically uraemic rats. | 2005-08 |
|
| Characterization of a transient covalent adduct formed during dimethylarginine dimethylaminohydrolase catalysis. | 2005-05-10 |
|
| Brain neuronal nitric oxide synthase neuron-mediated sympathoinhibition is enhanced in hypertensive Dahl rats. | 2005-04 |
|
| Interaction of central Ang II and NO on the cardiac sympathetic afferent reflex in dogs. | 2005-03-31 |
|
| Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina. | 2005-03-14 |
|
| Effects of renal nerve stimulation on intrarenal blood flow in rats with intact or inactivated NO synthases. | 2005-01 |
|
| Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase. | 1997 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:51:34 GMT 2025
by
admin
on
Mon Mar 31 19:51:34 GMT 2025
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| Record UNII |
M790X706JV
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| Record Status |
Validated (UNII)
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| Record Version |
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90712
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DTXSID00935505
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156719-41-4
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M790X706JV
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107968
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