Lucorafusp Alfa

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 16:52:02 GMT 2025` Edited by `admin` on `Wed Apr 02 16:52:02 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	M55KSH2AGH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Lucorafusp Alfa

Common Name

English

AK-130

Preferred Name

English

gamma 4 heavy chain (1-447) [VH (Homo sapiens IGHV4-30-4*01 -(IGHD) -IGHJ4*01, CDR-Kabat [6.16.12] (31-36.51-66.99-110)) (1-121) -Homo sapiens IGHG4*01 (CH1 (122-219), hinge S229>P (220-231), CH2 F235>A, L236>A (232-341),

Common Name

English

Immunoglobulin G4 [229-proline,235-alanine,236-alanine,476-threonine,de-468-lysine], anti-(human receptor TIGIT) (human-Mus musculus monoclonal AK130 ?4-chain) fusion protein with peptide linker ((GGGGS)4G) fusion protein with 2-137-transforming growth f

Common Name

English

humanized immunoglobulin G4-kappa, anti-[human TIGIT (T cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)] fused at the C-terminus of the heavy chain, via a (G4S)4 peptide linker, to a fragmen

Common Name

English

lucorafusp alfa [INN]

Common Name

English

AK130

Code

English

Code System Code Type Description

CAS

2769742-99-4