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Details

Stereochemistry ACHIRAL
Molecular Formula C23H25I2NO3
Molecular Weight 617.2584
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DESETHYLAMIODARONE

SMILES

CCCCC1=C(C(=O)C2=CC(I)=C(OCCNCC)C(I)=C2)C3=CC=CC=C3O1

InChI

InChIKey=VXOKDLACQICQFA-UHFFFAOYSA-N
InChI=1S/C23H25I2NO3/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C23H25I2NO3
Molecular Weight 617.2584
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of triiodothyronine and amiodarone on the promoter of the human LDL receptor gene.
1998 Aug 19
Amiodarone induces apoptosis of human and rat alveolar epithelial cells in vitro.
2000 May
Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence.
2003 Feb
The effect of beta-naphthoflavone on the metabolism of amiodarone by hepatic and extra-hepatic microsomes.
2010 Jun 2
Substance Class Chemical
Created
by admin
on Fri Jul 07 00:12:00 UTC 2023
Edited
by admin
on Fri Jul 07 00:12:00 UTC 2023
Record UNII
M31FU99E3Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DESETHYLAMIODARONE
Common Name English
AMIODARONE RELATED COMPOUND D [USP-RS]
Common Name English
Desethylaminodarone [WHO-DD]
Common Name English
N-DEETHYLAMIODARONE
Common Name English
(2-BUTYLBENZOFURAN-3-YL)(4-(2-(ETHYLAMINO)ETHOXY)-3,5-DIIODOPHENYL)METHANONE
Systematic Name English
AMIODARONE RELATED COMPOUND D
Common Name English
LB 33020
Code English
DEETHYLAMIODARONE
Common Name English
AMIODARONE METABOLITE M7
Common Name English
N-MONODESETHYLAMIODARONE
Common Name English
DESETHYLAMINODARONE
WHO-DD  
Common Name English
LB-33020
Code English
N-DESETHYLAMIODARONE
Common Name English
METHANONE, (2-BUTYL-3-BENZOFURANYL)(4-(2-(ETHYLAMINO)ETHOXY)-3,5-DIIODOPHENYL)-
Systematic Name English
AMIODARONE HYDROCHLORIDE IMPURITY B [EP IMPURITY]
Common Name English
DAMI
Common Name English
Code System Code Type Description
MESH
C036116
Created by admin on Fri Jul 07 00:12:01 UTC 2023 , Edited by admin on Fri Jul 07 00:12:01 UTC 2023
PRIMARY
EPA CompTox
DTXSID00232344
Created by admin on Fri Jul 07 00:12:01 UTC 2023 , Edited by admin on Fri Jul 07 00:12:01 UTC 2023
PRIMARY
CAS
83409-32-9
Created by admin on Fri Jul 07 00:12:01 UTC 2023 , Edited by admin on Fri Jul 07 00:12:01 UTC 2023
PRIMARY
RS_ITEM_NUM
1027346
Created by admin on Fri Jul 07 00:12:01 UTC 2023 , Edited by admin on Fri Jul 07 00:12:01 UTC 2023
PRIMARY
FDA UNII
M31FU99E3Y
Created by admin on Fri Jul 07 00:12:01 UTC 2023 , Edited by admin on Fri Jul 07 00:12:01 UTC 2023
PRIMARY
PUBCHEM
104774
Created by admin on Fri Jul 07 00:12:01 UTC 2023 , Edited by admin on Fri Jul 07 00:12:01 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> METABOLITE ACTIVE
MAJOR
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP