Bezetabart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:05:26 GMT 2023` Edited by `admin` on `Sat Dec 16 15:05:26 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	M00ALT7DTN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Bezetabart

Official Name

English

SP7219

Code

English

bezetabart [INN]

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CD74 (major histocompatibility complex class II invariant chain)], monoclonal antibody, modified at two specific positions with reactive 4-(azidomethyl)-L -phenylalanine residues

Common Name

English

SP-7219

Code

English

Immunoglobulin G1 [411-(4-azidomethyl-L-phenylalanine)], anti-(human CD74 antigen) (human monoclonal SP7219 γ1-chain), disulfide with human monoclonal SP7219 κ-chain, dimer

Common Name

English

Gamma1 heavy chain (1-454) [VH (Homo sapiens IGHV3-30-5*03 (95.9%) -(IGHD) -IGHJ6*01 (93.8%), CDR-IMGT [8.8.16] (27-34.52-59.98-113)) (1-124) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (221) (125-222), hinge 1-15 (223-2

Common Name

English

Code System Code Type Description

INN

12653

Created by admin on Sat Dec 16 15:05:26 GMT 2023 , Edited by admin on Sat Dec 16 15:05:26 GMT 2023

PRIMARY

CAS

2763746-69-4

Created by admin on Sat Dec 16 15:05:26 GMT 2023 , Edited by admin on Sat Dec 16 15:05:26 GMT 2023

PRIMARY

FDA UNII

M00ALT7DTN

Created by admin on Sat Dec 16 15:05:26 GMT 2023 , Edited by admin on Sat Dec 16 15:05:26 GMT 2023

PRIMARY

From	To
1_23	1_97
2_23	2_97
2_151	2_207
2_227	4_215
2_268	2_328
1_151	1_207
2_374	2_432
3_24	3_89
3_135	3_195
4_24	4_89
4_135	4_195
1_227	3_215
1_233	2_233
1_236	2_236
1_268	1_328
1_374	1_432

Related Record Type Details


					3AN44I0G7D

HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN

TARGET->LIGAND

Amount:

Related Record Type Details


					M00ALT7DTN

Bezetabart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL