RAZOBAZAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H14N4O2
Molecular Weight	270.2866
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C2=C(N(C3=CC=CC=C3)C(=O)CC1=O)C(C)=NN2

InChI

InChIKey=RHZDHINXKVZTEF-UHFFFAOYSA-N

InChI=1S/C14H14N4O2/c1-9-13-14(16-15-9)17(2)11(19)8-12(20)18(13)10-6-4-3-5-7-10/h3-7H,8H2,1-2H3,(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C14H14N4O2
Molecular Weight	270.2866
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3814045 | https://www.ncbi.nlm.nih.gov/pubmed/3927347

Razobazam (Hoe 175) is a benzodiazepine derivative. Benzodiazepines are mainly used for treatment of anxiety. Razobazam improves learning performance in socially deprived rats. A 13% increase in neuronal density in the frontal cortex (associated with complex cognitive functions) of rats treated with razobazam was observed, but no changes in the amygdala (involved in emotion and memory functions). In mice, razobazam also affects retention performance through influences on memory storage and retrieval.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:27:13 UTC 2023` Edited by `admin` on `Fri Dec 15 16:27:13 UTC 2023`
Record UNII	LZ84VWN0U4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RAZOBAZAM

Official Name

English

razobazam [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756