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Details

Stereochemistry ACHIRAL
Molecular Formula C12H12N2.2ClH
Molecular Weight 257.159
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENZIDINE DIHYDROCHLORIDE

SMILES

Cl.Cl.NC1=CC=C(C=C1)C2=CC=C(N)C=C2

InChI

InChIKey=RUAXWVDEYJEWRY-UHFFFAOYSA-N
InChI=1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C12H12N2
Molecular Weight 184.2371
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Accessibility of tyrosine Y(.)(Z) to exogenous reductants and Mn(2+) in various Photosystem II preparations.
2001 Apr 2
Studies of a disposable biosensor based on the beta-cyclodextrin inclusion complex as mediator.
2001 Dec 1
New reagents for detection of faecal occult blood.
2001 Feb
Trace-level determination of benzidine and 3,3'-dichlorobenzidine in aqueous environmental samples by online solid-phase extraction and liquid chromatography with electrochemical detection.
2001 Jul
Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate.
2001 Jun 15
Dependence of papanicolaou gradings of exfoliated urothelial cells upon GSTM1 and GSTT1 polymorphism in benzidine-exposed workers of the Shanghai dye industry.
2001 Nov
Biological monitoring in workers in a nitrobenzene reduction plant: haemoglobin versus serum albumin adducts.
2001 Sep
Dyes metabolized to benzidine (benzidine dye class).
2002
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation.
2002 Apr 25
Carcinogen biomonitoring in human exposures and laboratory research: validation and application to human occupational exposures.
2002 Aug 5
Imipramine hydrochloride and desipramine hydrochloride as new reagents for detection of microamounts of blood in urine.
2002 May 15
Biodegradation of benzidine based azodyes Direct red and Direct blue by the immobilized cells of Pseudomonas fluorescens D41.
2002 Oct
Semiconductor-mediated photocatalysed degradation of two selected priority organic pollutants, benzidine and 1,2-diphenylhydrazine, in aqueous suspension.
2002 Oct
Polymorphism of glutathione S-transferase T1, M1 and P1 genes in a Shanghai population: patients with occupational or non-occupational bladder cancer.
2002 Sep
Occupational exposure and urological cancer.
2004 Feb
Biomarkers in maternal and newborn blood indicate heightened fetal susceptibility to procarcinogenic DNA damage.
2004 Jul
Surface-modified mesoporous ceramics as delivery vehicle for haemoglobin.
2004 May-Jun
Listing occupational carcinogens.
2004 Nov
Overexpression of transglutaminase 2 accelerates the erythroid differentiation of human chronic myelogenous leukemia K562 cell line through PI3K/Akt signaling pathway.
2004 Nov 19
Production of hemo- and immunoregulatory cytokines by erythroblast antigen+ and glycophorin A+ cells from human bone marrow.
2004 Oct 18
Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer.
2004 Oct 6
[Determination of deoxyribonuceic acids by resonance light scattering technique with benzidine in the presence of the sensitizing sodium dodecyl sulfate].
2004 Sep
[Expression of protein p53 in workers occupationally exposed to benzidine and bladder cancer patients.].
2005 Feb
The formation of cucurbit[n]uril (n = 6, 7) complexes with amino compounds in aqueous formic acid studied by capillary electrophoresis.
2005 Jun
Annexin1 regulates the erythroid differentiation through ERK signaling pathway.
2005 Jun 17
An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China.
2005 May
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:50:02 GMT 2023
Edited
by admin
on Fri Dec 15 18:50:02 GMT 2023
Record UNII
LVU06XHC39
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BENZIDINE DIHYDROCHLORIDE
Systematic Name English
(1,1'-BIPHENYL)-4,4'-DIAMINE, DIHYDROCHLORIDE
Common Name English
NSC-3500
Code English
(1,1'-BIPHENYL)-4,4'-DIAMINE, HYDROCHLORIDE (1:2)
Systematic Name English
BENZIDINE HCL
Common Name English
Code System Code Type Description
CAS
531-85-1
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
CAS
14414-68-7
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
NON-SPECIFIC STOICHIOMETRY
ECHA (EC/EINECS)
208-519-6
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
NSC
3500
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
MESH
C029876
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
EPA CompTox
DTXSID7020138
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
PUBCHEM
10754
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
FDA UNII
LVU06XHC39
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE