BENZIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H12N2
Molecular Weight	184.2371
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=CC=C(C=C1)C2=CC=C(N)C=C2

InChI

InChIKey=HFACYLZERDEVSX-UHFFFAOYSA-N

InChI=1S/C12H12N2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8H,13-14H2

HIDE SMILES / InChI

Molecular Formula	C12H12N2
Molecular Weight	184.2371
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Epidemiology and etiology of premalignant and malignant urothelial changes.	2000	11144890
Accessibility of tyrosine Y(.)(Z) to exogenous reductants and Mn(2+) in various Photosystem II preparations.	2001 Apr 2	11245806
Re-evaluation of the latent period of bladder cancer in dyestuff-plant workers in Japan.	2001 Aug	11555006
Studies of a disposable biosensor based on the beta-cyclodextrin inclusion complex as mediator.	2001 Dec 1	11726186
Carcinogen substrate specificity of human COX-1 and COX-2.	2001 Jan	11159734
Biomarker risk assessment and bladder cancer detection in a cohort exposed to benzidine.	2001 Mar 21	11259468
Biological monitoring in workers in a nitrobenzene reduction plant: haemoglobin versus serum albumin adducts.	2001 Sep	11697451
Dyes metabolized to benzidine (benzidine dye class).	2002	15318373
A search for colocalization of mglula receptors with CRF or NPY in the rat brain amygdala.	2002	12056621
How many food additives are rodent carcinogens?	2002	11813298
Nonassociation of aryl hydrocarbon receptor genotypes with susceptibility to bladder cancer in Shanghai population.	2002 Feb	11866883
Co-transfection of p16(INK4a) and p53 genes into the K562 cell line inhibits cell proliferation.	2002 Feb	11836163
[Experimental study on effect of Angelica polysaccharide in inhibitory proliferation and inducing differentiation of K562 cells].	2002 Jan	12585175
Biodegradation of benzidine based azodyes Direct red and Direct blue by the immobilized cells of Pseudomonas fluorescens D41.	2002 Oct	12693692
Mutant spectra analysis at hisG46 in Salmonella typhimurium strain YG1029 induced by mammalian S9- and plant-activated aromatic amines.	2003	12616596
Growth inhibition of intestinal bacteria and mutagenicity of 2-, 3-, 4-aminobiphenyls, benzidine, and biphenyl.	2003 Apr	12650667
Immobilization of thermolysin to polyamide nonwoven materials.	2003 Apr 20	12584760
Appearance of erythrocyte-like globules in the mouse visceral yolk sac endodermal cells on embryonic day 12, with special reference to blood islands.	2003 Jun	12801082
Amperometric biosensors based on recombinant laccases for phenols determination.	2003 Mar	12485779
[Homozygous hemoglobin constant spring in Guangxi province].	2004 Apr	15182556
Age-related differences in susceptibility to carcinogenesis: a quantitative analysis of empirical animal bioassay data.	2004 Aug	15289159
Optimization of an analytical method for detecting paraphenylenediamine (PPD) by GC/MS-iontrap in biological liquids.	2004 Dec 2	15639598
Oxidation of benzidine and its derivatives by thyroid peroxidase.	2004 Feb	15000688
Biomarkers in maternal and newborn blood indicate heightened fetal susceptibility to procarcinogenic DNA damage.	2004 Jul	15238289
Carcinogenicity of azo colorants: influence of solubility and bioavailability.	2004 Jun 15	15177655
Production of hemo- and immunoregulatory cytokines by erythroblast antigen+ and glycophorin A+ cells from human bone marrow.	2004 Oct 18	15488155
Chemical and enzymatic interactions of Direct Black 38 and Direct Brown 1 on release of carcinogenic amines.	2004 Sep	15261529
Localization of sulfated sialic acids in the dentinal tubules during tooth formation in mice.	2005	15866285
Morphology, cytochemical staining, and ultrastructural characteristics of the blood cells of the giant lizard of El Hierro (Gallotia simonyi).	2005 Apr	15563919
Concentrations and distribution of 3,3'-dichlorobenzidine and its congeners in environmental samples from Lake Macatawa.	2005 Feb	15621190
[Effect of specific siRNA targeting against bcr-abl chimeric gene on chronic myelogenous leukemia cells].	2005 Jan 19	15854468

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:50:01 GMT 2023` Edited by `admin` on `Fri Dec 15 18:50:01 GMT 2023`
Record UNII	2X02101HVF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BENZIDINE

Systematic Name

English

P-DIAMINODIPHENYL

Common Name

English

NSC-146476

Code

English

PHENYLBUTAZONE IMPURITY E [EP IMPURITY]

Common Name

English

(1,1'-BIPHENYL)-4,4'-DIAMINE

Systematic Name

English

NCI-C03361

Code

English

BENZIDINE [MI]

Common Name

English

BENZIDINE, DYES METABOLIZED TO [IARC]

Common Name

English

BENZIDINE [IARC]

Common Name

English

BENZIDINE [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45178