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Details

Stereochemistry ACHIRAL
Molecular Formula C11H8I3NO4
Molecular Weight 598.8989
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DOCETRIZOATE

SMILES

CC(=O)N(C(C)=O)C1=C(I)C(C(O)=O)=C(I)C=C1I

InChI

InChIKey=GGOPTDHVLCAOSV-UHFFFAOYSA-N
InChI=1S/C11H8I3NO4/c1-4(16)15(5(2)17)10-7(13)3-6(12)8(9(10)14)11(18)19/h3H,1-2H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula C11H8I3NO4
Molecular Weight 598.8989
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Docetrizoate (trade name: Pulmidol) is the bronchographic agent (radiopaque medium). The most important characteristic of a bronchographic medium, that it should flow readily into small bronchial branches, but not pass into bronchioles, is well fulfilled by Pulmidol. Propyl docetrizoate in 60 or 75 per cent suspension in arachis oil produced satisfactory bronchograms in the cat and in man. The radio-opaque material was cleared from the lung within two to four days, and produced no significant histological changes in the lungs of cats receiving a high concentration into one lobe. Early in 1962 a change to Pulmidol was made because of the increased contrast due to its higher iodine content, but its use had to be discontinued following reports of deaths in children due to its absorption under anaesthesia.

Approval Year

PubMed

Substance Class Chemical
Record UNII
LUJ212Y57D
Record Status Validated (UNII)
Record Version