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Details

Stereochemistry ACHIRAL
Molecular Formula C11H8I3NO4
Molecular Weight 598.8989
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DOCETRIZOATE

SMILES

CC(=O)N(C(C)=O)C1=C(I)C(C(O)=O)=C(I)C=C1I

InChI

InChIKey=GGOPTDHVLCAOSV-UHFFFAOYSA-N
InChI=1S/C11H8I3NO4/c1-4(16)15(5(2)17)10-7(13)3-6(12)8(9(10)14)11(18)19/h3H,1-2H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula C11H8I3NO4
Molecular Weight 598.8989
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Docetrizoate (trade name: Pulmidol) is the bronchographic agent (radiopaque medium). The most important characteristic of a bronchographic medium, that it should flow readily into small bronchial branches, but not pass into bronchioles, is well fulfilled by Pulmidol. Propyl docetrizoate in 60 or 75 per cent suspension in arachis oil produced satisfactory bronchograms in the cat and in man. The radio-opaque material was cleared from the lung within two to four days, and produced no significant histological changes in the lungs of cats receiving a high concentration into one lobe. Early in 1962 a change to Pulmidol was made because of the increased contrast due to its higher iodine content, but its use had to be discontinued following reports of deaths in children due to its absorption under anaesthesia.

Approval Year

PubMed

PubMed

TitleDatePubMed
BRONCHOGRAPHIC CONTRAST MEDIUMS.
1962-11
Properties of a new contrast medium for bronchography: n-propyl 2, 4, 6-triiodo-3-diacetamidobenzoate (propyl docetrizoate).
1961-11
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:37:18 GMT 2025
Edited
by admin
on Mon Mar 31 22:37:18 GMT 2025
Record UNII
LUJ212Y57D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DOCETRIZOATE
Common Name English
3-DIACETYLAMINO-2,4,6-TRIIODOBENZOATE
Preferred Name English
BENZOIC ACID, 3-(DIACETYLAMINO)-2,4,6-TRIIODO-
Systematic Name English
Code System Code Type Description
FDA UNII
LUJ212Y57D
Created by admin on Mon Mar 31 22:37:18 GMT 2025 , Edited by admin on Mon Mar 31 22:37:18 GMT 2025
PRIMARY
CAS
10311-24-7
Created by admin on Mon Mar 31 22:37:18 GMT 2025 , Edited by admin on Mon Mar 31 22:37:18 GMT 2025
PRIMARY
PUBCHEM
21438009
Created by admin on Mon Mar 31 22:37:18 GMT 2025 , Edited by admin on Mon Mar 31 22:37:18 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY