U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2018
436
Substance Class Protein
Created
by admin
on Sat Dec 16 00:10:43 UTC 2023
Edited
by admin
on Sat Dec 16 00:10:43 UTC 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
LT369U66CE
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
IBALIZUMAB, LICENSE HOLDER UNSPECIFIED
Preferred Name English
IBALIZUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
TNX-355
Code English
IMMUNOGLOBULIN G4, ANTI-(HUMAN CD4 (ANTIGEN)) (HUMAN-MOUSE MONOCLONAL 5A8 .GAMMA.4-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL 5A8 .KAPPA.-CHAIN, DIMER
Common Name English
ibalizumab [INN]
Common Name English
Ibalizumab-uiyk [WHO-DD]
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN CD4 (ANTIGEN)) (HUMAN-MOUSE MONOCLONAL 5A8 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL 5A8 .KAPPA.-CHAIN, DIMER
Common Name English
Ibalizumab [WHO-DD]
Common Name English
IBALIZUMAB [USAN]
Common Name English
IBALIZUMAB [MI]
Common Name English
Classification Tree Code System Code
WHO-ATC J05AX23
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
FDA ORPHAN DRUG 70692
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
FDA ORPHAN DRUG 321910
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
Code System Code Type Description
WIKIPEDIA
Hexamethylphosphoramide
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
EVMPD
SUB130719
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
ALTERNATIVE
FDA UNII
LT369U66CE
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
SMS_ID
100000168847
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
DRUG BANK
DB12698
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
EVMPD
SUB182421
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
ChEMBL
CHEMBL1743029
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
DAILYMED
LT369U66CE
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
RXCUI
2043313
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
ALTERNATIVE
LACTMED
Ibalizumab
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
MERCK INDEX
m12068
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
DRUG CENTRAL
5279
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
NCI_THESAURUS
C88612
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
CAS
680188-33-4
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
RXCUI
2043283
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
INN
8818
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
EPA CompTox
DTXSID601028049
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
USAN
SS-01
Created by admin on Sat Dec 16 00:10:43 UTC 2023 , Edited by admin on Sat Dec 16 00:10:43 UTC 2023
PRIMARY
From To
1_22 1_96
1_136 3_219
1_149 1_205
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
2_22 2_96
2_136 4_219
2_149 2_205
2_263 2_323
2_369 2_427
3_23 3_94
3_139 3_199
4_23 4_94
4_139 4_199
Related Record Type Details
T-CELL SURFACE GLYCOPROTEIN CD4
TARGET -> INHIBITOR
Blocks HIV infection. Used against MDR HIV Strains
IBALIZUMAB-UIYK [PURPLE BOOK CDER]
INNOVATOR->PARENT
IBALIZUMAB-UIYK [PURPLE BOOK CDER]
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
IBALIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Molecular Formula CHEMICAL
MOL_WEIGHT:ESTIMATED CHEMICAL
Biological Half-life PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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