BENZOTRIPT

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H15ClN2O3
Molecular Weight	342.776
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BENZOTRIPT

Structure Search

SMILES

OC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3

InChI

InChIKey=QJERBBQXOMUURJ-INIZCTEOSA-N

InChI=1S/C18H15ClN2O3/c19-13-7-5-11(6-8-13)17(22)21-16(18(23)24)9-12-10-20-15-4-2-1-3-14(12)15/h1-8,10,16,20H,9H2,(H,21,22)(H,23,24)/t16-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H15ClN2O3
Molecular Weight	342.776
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6320314

Benzotript, a cholecystokinin antagonist is an anti-gastrinic.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Cholecystokinin antagonists proglumide, lorglumide and benzotript, but not L-364,718, interact with brain opioid binding sites.	1990-05	2174522
Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin.	1985-05	2984080
Evidence that proglumide and benzotript antagonize secretagogue stimulation of isolated gastric parietal cells.	1983-11	6320314
Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists.	1981-10	6171817

Patents

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:32:15 GMT 2025` Edited by `admin` on `Wed Apr 02 08:32:15 GMT 2025`
Record UNII	LS5O682BRO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENZOTRIPT

Official Name

English

N-(P-CHLOROBENZOYL)-L-TRYPTOPHAN

Preferred Name

English

benzotript [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

Code System Code Type Description

PUBCHEM

2060890

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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NCI_THESAURUS

C76479

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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FDA UNII

LS5O682BRO

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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ChEMBL

CHEMBL63544

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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MESH

C013841

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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SMS_ID

100000086390

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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INN

3700

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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EVMPD

SUB05762MIG

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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EPA CompTox

DTXSID501043305

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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CAS

39544-74-6

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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ECHA (EC/EINECS)

254-500-0

Created by admin on Wed Apr 02 08:32:15 GMT 2025 , Edited by admin on Wed Apr 02 08:32:15 GMT 2025

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					LS5O682BRO

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