CHROMIC CITRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H5O7.Cr
Molecular Weight	241.0958
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cr+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

InChIKey=SWXXYWDHQDTFSU-UHFFFAOYSA-K

InChI=1S/C6H8O7.Cr/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3

HIDE SMILES / InChI

Molecular Formula	C6H5O7
Molecular Weight	189.0997
Charge	-3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Cr
Molecular Weight	51.9961
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10630581 | https://www.ncbi.nlm.nih.gov/pubmed/28954488

Chromium sulfate(III) hexahydrate or chromium sulphate, a trivalent compound of chromium that was investigated as a toxic compound. Experiments on rodent have shown chromium sulfate produced severe and widespread effects in the nasal cavity, larynx, lungs, and mediastinal lymph node. Effects were characterized by the accumulation of foreign material, infiltration of alveolar macrophages, septal cell hyperplasia, and granulomatous and chronic inflammation. Besides, chromium sulphate exerted a disadvantageous effect on the skeleton, as it decreases bone density and resistance.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
transmembrane receptor protein tyrosine kinase activity 22 Target ID: GO:0004714 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15924436	Activator 1430

Conditions

Condition	Modality	Targets	Highest Phase	Product
Chromium deficiency 22 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4d01ebb-a36e-44b7-028c-43c0ab2d13b4	Preventing		Approved 8429	CHROMIUM Approved Use Chromium 4 mcg/mL (Chromic Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition. Administration helps to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms. Launch Date 1.12000316E12

PubMed

Title	Date	PubMed
Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin.	1994 Jun	8006454
Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium.	2007 Aug	17606337

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:51:54 UTC 2023` Edited by `admin` on `Fri Dec 15 19:51:54 UTC 2023`
Record UNII	LQC76G8WUE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHROMIC CITRATE

Common Name

English

CHROMIUM(3+) CITRATE

Systematic Name

English

CITRIC ACID, CHROMIUM SALT

Common Name

English

CHROMIUM(III) CITRATE

Systematic Name

English

Chromium(III) citrate [WHO-DD]

Common Name

English

1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, CHROMIUM(3+) SALT (1:1)

Systematic Name

English

1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, CHROMIUM(3+) SALT

Systematic Name

English

CHROMIUM CITRATE

Systematic Name

English

Code System Code Type Description

PUBCHEM

6453431