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Details

Stereochemistry RACEMIC
Molecular Formula C20H20ClN5O3S2
Molecular Weight 477.988
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SURICLONE

SMILES

CN1CCN(CC1)C(=O)OC2N(C(=O)C3=C2SCCS3)C4=CC=C5C=CC(Cl)=NC5=N4

InChI

InChIKey=RMXOUBDDDQUBKD-UHFFFAOYSA-N
InChI=1S/C20H20ClN5O3S2/c1-24-6-8-25(9-7-24)20(28)29-19-16-15(30-10-11-31-16)18(27)26(19)14-5-3-12-2-4-13(21)22-17(12)23-14/h2-5,19H,6-11H2,1H3

HIDE SMILES / InChI

Molecular Formula C20H20ClN5O3S2
Molecular Weight 477.988
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Suriclone is a dithiinopyrrole derivative patented by Rhone-Poulenc S. A. as a sedative and anxiolytic drug. The mechanism of action by which suriclone produces it's sedative and anxiolytic effects is by modulating GABAA receptors, although suriclone is more subtype-selective than most benzodiazepines. In clinical trials, Suriclone shows a significant anxiolytic effect. The most common adverse reaction was dizziness.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
0.1, 0.2 and 0.4 mg
Route of Administration: Oral
Substance Class Chemical
Record UNII
LNC9G689VR
Record Status Validated (UNII)
Record Version