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Details

Stereochemistry RACEMIC
Molecular Formula C17H15FN2O3
Molecular Weight 314.311
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FENLEUTON

SMILES

CC(C#CC1=CC(OC2=CC=C(F)C=C2)=CC=C1)N(O)C(N)=O

InChI

InChIKey=MWXPQCKCKPYBDR-UHFFFAOYSA-N
InChI=1S/C17H15FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-4,7-12,22H,1H3,(H2,19,21)

HIDE SMILES / InChI
Molecular Formula C17H15FN2O3
Molecular Weight 314.311
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

FENLEUTON is a potent, reversible and selective inhibitor of 5-lipoxygenase with IC50 values ranging from 80 to 1100 nM. It was studied for potential use in veterinary medicine to treat chronic obstructive pulmonary disease in horses.

Originator

Abbott Laboratories
27

Approval Year

Unknown
139,594

PubMed

Patents

05714633
5
20020111495
5
20050049258
2
20050222160
1
Substance Class Chemical
Record UNII
LG64454O6I
Record Status Validated (UNII)
Record Version
NIH
NCATS
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