3-AMINO-1,4-DIMETHYL-5H-PYRIDO(4,3-B)INDOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H13N3
Molecular Weight	211.2624
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 3-AMINO-1,4-DIMETHYL-5H-PYRIDO(4,3-B)INDOLE

SMILES

CC1=NC(N)=C(C)C2=C1C3=CC=CC=C3N2

InChI

InChIKey=LVTKHGUGBGNBPL-UHFFFAOYSA-N

InChI=1S/C13H13N3/c1-7-12-11(8(2)15-13(7)14)9-5-3-4-6-10(9)16-12/h3-6,16H,1-2H3,(H2,14,15)

HIDE SMILES / InChI

Molecular Formula	C13H13N3
Molecular Weight	211.2624
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Show entries

Title	Date	PubMed
Carcinogenicity in mice and rats of heterocyclic amines in cooked foods.	1986 Aug	3757948
Antagonism of gamma-aminobutyric acidA receptor-mediated responses by amino-gamma-carbolines.	1990 Mar	2156996
Effects of beta- and gamma-carboline derivatives of DNA topoisomerase activities.	1996 Feb 1	8600349
Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food.	2002 Dec	12974398
Evoking cytochrome P450 1A activity interferes with apoptosis induced by 3-amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) in rat hepatocytes under the ex vivo system.	2002 Feb	11999409

Showing 1 to 5 of 13 entries

Previous1 2 3Next

Patents

Substance Class	Chemical
Record UNII	LAH2R5Z22D
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

3-AMINO-1,4-DIMETHYL-5H-PYRIDO(4,3-B)INDOLE

Systematic Name

English

TRP-P-1

Common Name

English

3-AMINO-1,4-DIMETHYL-.GAMMA.-CARBOLINE

Common Name

English

TRYPTOPHAN P 1

Common Name

English

5H-PYRIDO(4,3-B)INDOL-3-AMINE, 1,4-DIMETHYL-

Systematic Name

English

Showing 1 to 5 of 9 entries

Previous1 2Next

Show entries

Code System

Code

Type

Description

EPA CompTox

DTXSID0043767

PRIMARY

PUBCHEM

5284474

PRIMARY

CAS

62450-06-0

PRIMARY

FDA UNII

LAH2R5Z22D

PRIMARY

Showing 1 to 4 of 4 entries

Previous1Next

Show entries

Related Record

Type

Details


					MLC2P2T92G

JAPANESE SCAD, COOKED

PARENT -> CONSTITUENT ALWAYS PRESENT

Comments:

Heterocyclic amine skin content in cooked food sample. 216?26 pg/g sample.


					MLC2P2T92G

JAPANESE SCAD, COOKED

PARENT -> CONSTITUENT ALWAYS PRESENT

Comments:

Semi-Dried(Aji-Hiraki) JAPANESE HORSE MACKEREL SKIN, COOKED Heterocyclic amine skin content in cooked food sample. 278?37 pg/g sample.


					ZPM81K61U4

CHICKEN, COOKED

PARENT -> CONSTITUENT ALWAYS PRESENT

Comments:

Heterocyclic amine in cooked meat sample. 527?96 pg/g sample.


					2C364ER602

CHUM SALMON, COOKED

PARENT -> CONSTITUENT ALWAYS PRESENT

Comments:

Heterocyclic amine skin content in cooked food sample. 289?38 pg/g sample.

Showing 1 to 4 of 4 entries

Previous1Next