Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C18H10I6N2O7.2C7H17NO5 |
Molecular Weight | 1518.1352 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)C1=C(I)C=C(I)C(NC(=O)COCC(=O)NC2=C(I)C(C(O)=O)=C(I)C=C2I)=C1I
InChI
InChIKey=HHFDMOXEMINUNX-VRWDCWMNSA-N
InChI=1S/C18H10I6N2O7.2C7H17NO5/c19-5-1-7(21)15(13(23)11(5)17(29)30)25-9(27)3-33-4-10(28)26-16-8(22)2-6(20)12(14(16)24)18(31)32;2*1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H,3-4H2,(H,25,27)(H,26,28)(H,29,30)(H,31,32);2*4-13H,2-3H2,1H3/t;2*4-,5+,6+,7+/m.00/s1
Molecular Formula | C7H17NO5 |
Molecular Weight | 195.2136 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Molecular Formula | C18H10I6N2O7 |
Molecular Weight | 1127.708 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Ioglycamate is triiodocarboxyanilide derivative patented by Schering A.-G. as intravenous cholangiographic X-ray contrast media. Meglumine ioglycamate and was marketed in South Africa in 1976 under brand name Biligram. Ioglycamate is rapidly eliminated from human blood where approximately 95% of the administered dose is bound to the plasma proteins. The mean plasma half-life is 30 minutes. Tbe compound is not metabolised to any great extent but most is eliminated a unchanged molecules with the faeces. In clinical trials good to excellent opacification was achieved in 69% of all patients. A total of 17% of all patients showed side-effects, the majority of which were transient and of a minor nature. Blood pressure and liver function were apparently not affected
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1006474
17 g/I00 ml infused at a constant rate over 30 minute
Route of Administration:
Intravenous
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:37:40 GMT 2023
by
admin
on
Fri Dec 15 18:37:40 GMT 2023
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Record UNII |
L9D9Y4YULV
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Record Status |
Validated (UNII)
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Record Version |
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-
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29897-96-9
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NON-SPECIFIC STOICHIOMETRY | |||
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14317-18-1
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m6364
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100000086429
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L9D9Y4YULV
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SUB02749MIG
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159736
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DTXSID60162330
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admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
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