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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H10I6N2O7.2C7H17NO5
Molecular Weight 1518.1352
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IOGLYCAMATE MEGLUMINE

SMILES

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)C1=C(I)C=C(I)C(NC(=O)COCC(=O)NC2=C(I)C(C(O)=O)=C(I)C=C2I)=C1I

InChI

InChIKey=HHFDMOXEMINUNX-VRWDCWMNSA-N
InChI=1S/C18H10I6N2O7.2C7H17NO5/c19-5-1-7(21)15(13(23)11(5)17(29)30)25-9(27)3-33-4-10(28)26-16-8(22)2-6(20)12(14(16)24)18(31)32;2*1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H,3-4H2,(H,25,27)(H,26,28)(H,29,30)(H,31,32);2*4-13H,2-3H2,1H3/t;2*4-,5+,6+,7+/m.00/s1

HIDE SMILES / InChI

Molecular Formula C7H17NO5
Molecular Weight 195.2136
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula C18H10I6N2O7
Molecular Weight 1127.708
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ioglycamate is triiodocarboxyanilide derivative patented by Schering A.-G. as intravenous cholangiographic X-ray contrast media. Meglumine ioglycamate and was marketed in South Africa in 1976 under brand name Biligram. Ioglycamate is rapidly eliminated from human blood where approximately 95% of the administered dose is bound to the plasma proteins. The mean plasma half-life is 30 minutes. Tbe compound is not metabolised to any great extent but most is eliminated a unchanged molecules with the faeces. In clinical trials good to excellent opacification was achieved in 69% of all patients. A total of 17% of all patients showed side-effects, the majority of which were transient and of a minor nature. Blood pressure and liver function were apparently not affected

Approval Year

PubMed

PubMed

TitleDatePubMed
A clinical and radiological trial of meglumine loglycamate, a new intravenous cholangiographic contrast medium.
1976 Nov 20
Patents

Patents

Sample Use Guides

17 g/I00 ml infused at a constant rate over 30 minute
Route of Administration: Intravenous
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:37:40 GMT 2023
Edited
by admin
on Fri Dec 15 18:37:40 GMT 2023
Record UNII
L9D9Y4YULV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IOGLYCAMATE MEGLUMINE
WHO-DD  
Common Name English
IOGLYCAMIC ACID MEGLUMINE SALT [MI]
Common Name English
BILIGRAM
Common Name English
METHYLGLUCAMINE IOGLYCAMIDE
Common Name English
IOGLYCAMIC ACID MEGLUMINE SALT
MI  
Common Name English
Ioglycamate meglumine [WHO-DD]
Common Name English
GLUCITOL, 1-DEOXY-1-(METHYLAMINO)-, 3,3'-(OXYBIS(METHYLENECARBONYLIMINO))BIS(2,4,6-TRIIODOBENZOATE) (2:1) (SALT), D-
Common Name English
BENZOIC ACID, 3,3'-(DIGLYCOLOYLDIIMINO)BIS(2,4,6-TRIIODO-, COMPD. WITH 1-DEOXY-1-(METHYLAMINO)GLUCITOL (1:2)
Common Name English
D-GLUCITOL, 1-DEOXY-1-(METHYLAMINO)-, 3,3'-(OXYBIS((1-OXO-2,1-ETHANEDIYL)IMINO))BIS(2,4,6-TRIIODOBENZOATE) (2:1)
Systematic Name English
Code System Code Type Description
CAS
29897-96-9
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
NON-SPECIFIC STOICHIOMETRY
CAS
14317-18-1
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY
MERCK INDEX
m6364
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY Merck Index
SMS_ID
100000086429
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY
FDA UNII
L9D9Y4YULV
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY
EVMPD
SUB02749MIG
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY
PUBCHEM
159736
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID60162330
Created by admin on Fri Dec 15 18:37:40 GMT 2023 , Edited by admin on Fri Dec 15 18:37:40 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE