ETHENZAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H11NO2
Molecular Weight	165.1891
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC1=C(C=CC=C1)C(N)=O

InChI

InChIKey=SBNKFTQSBPKMBZ-UHFFFAOYSA-N

InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11)

HIDE SMILES / InChI

Molecular Formula	C9H11NO2
Molecular Weight	165.1891
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.med.or.jp/english/pdf/2001_08/364_368.pdf

Ethenzamide is an anti-inflammatory agent that was used for the treatment of common cold in Japan (in combinations with other NSAIDs).

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Common cold 58 Sources: http://www.med.or.jp/english/pdf/2001_08/364_368.pdf	Primary		Approved 8429	NARON ACE Approved Use Unknown

PubMed

Title	Date	PubMed
Preparation and clinical application of 2% diflunisal oral ointment for painful lesions of the oral mucosa.	2001 Nov	11725552
Preparation of solid dispersion for ethenzamide-carbopol and theophylline-carbopol systems using a twin screw extruder.	2002 Jun	12045335
Cutaneous drug reaction case reports: from the world literature.	2003	12688840
Assessment of tableting properties using infinitesimal quantities of powdered medicine.	2003 Sep 16	12954193
Continuous grinding kinetics of ethenzamide particles by fluidized-bed jet-milling.	2006 Mar	16556539
Evaluation of rapidly disintegrating tablets containing glycine and carboxymethylcellulose.	2006 Mar 9	16434157
Dissolution characteristics of cylindrical particles and tablets.	2006 Mar 9	16414218
One-step preparation of drug-containing microparticles to enhance the dissolution and absorption of poorly water-soluble drugs using a 4-fluid nozzle spray drier.	2007 Jul 31	17582644
Evaluation of pharmaceuticals and personal care products as water-soluble molecular markers of sewage.	2008 Sep 1	18800500
Theophylline-gentisic acid (1/1).	2009 Aug 8	21577539
Distribution of ethenzamide and other ingredients on granule surfaces studied by Raman microspectroscopy and mapping.	2009 May	19530442
Development, characterization and solubility study of solid dispersions of azithromycin dihydrate by solvent evaporation method.	2010 Apr	22247849

Patents

Sample Use Guides

In Vivo Use Guide

2 pills containing 84 mg of ethenzamide 3 times a day.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:51:05 GMT 2023` Edited by `admin` on `Sat Dec 16 04:51:05 GMT 2023`
Record UNII	L929ZCK4BF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETHENZAMIDE

Official Name

English

Ethenzamide [WHO-DD]

Common Name

English

ETHENZAMIDE [MI]

Common Name

English

ETHENZAMIDE [JAN]

Common Name

English

O-ETHOXYBENZAMIDE

Common Name

English

ETENZAMIDE

Common Name

English

NSC-28787

Code

English

ethenzamide [INN]

Common Name

English

ETHOXYBENZAMIDE

Systematic Name

English

ETHENZAMIDE [MART.]

Common Name

English

J3.352I

Code

English

Classification Tree Code System Code

WHO-ATC

N02BA77