MOPROLOL HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H21NO3.ClH
Molecular Weight	275.772
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COC1=CC=CC=C1OCC(O)CNC(C)C

InChI

InChIKey=JKEZSJIWQWVVQR-UHFFFAOYSA-N

InChI=1S/C13H21NO3.ClH/c1-10(2)14-8-11(15)9-17-13-7-5-4-6-12(13)16-3;/h4-7,10-11,14-15H,8-9H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	C13H21NO3
Molecular Weight	239.3107
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/36116 | https://www.ncbi.nlm.nih.gov/pubmed/6120901

Moprolol is a beta-adrenergic antagonist, or beta blocker, typically prescribed to treat hypertension, high blood pressure, angina pectoris, arrhythmias, anxiety, and glaucoma. Moprolol has been the subject for many clinical trials to study the effect moprolol has on both blood pressure and glaucoma. In clinical trials, Moprolol shows some effect on lowering blood pressure with no effects on the heart rate. Moprolol is currently off the market, most likely due to the manufacturer being in violation of US good manufacturing practices.

Originator

Approval Year

PubMed

Title	Date	PubMed
[A case of giant cell microscopic colitis?].	2008-12	19084720
[Evaluation of the effects of a beta-blocking drug (moprolol) on hemodynamics and lesion potentials in acute myocardial infarct].	1977	36116

Patents

Sample Use Guides

In Vivo Use Guide

75 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:24:34 GMT 2025` Edited by `admin` on `Mon Mar 31 22:24:34 GMT 2025`
Record UNII	L42WT1PR63
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OMERAL

Preferred Name

English

MOPROLOL HYDROCHLORIDE

Common Name

English

1-(O-METHOXYPHENOXY)-3-ISOPROPYLAMINO-2-PROPANOL HYDROCHLORIDE

Common Name

English

D-1601

Code

English

MOPROLOL HYDROCHLORIDE [MI]

Common Name

English

Moprolol hydrochloride [WHO-DD]

Common Name

English

2-PROPANOL, 1-(2-METHOXYPHENOXY)-3-((1-METHYLETHYL)AMINO)-, HYDROCHLORIDE (1:1)

Systematic Name

English

SD-1601

Code

English

Code System Code Type Description

ECHA (EC/EINECS)

248-195-3