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Details

Stereochemistry UNKNOWN
Molecular Formula 2C22H27NO2.C4H4O4
Molecular Weight 790.9827
Optical Activity ( + )
Defined Stereocenters 0 / 2
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of DEXPROXIBUTENE MALEATE

SMILES

OC(=O)\C=C/C(O)=O.CCC(=O)OC(CC1=CC=CC=C1)(C(=C)CN(C)C)C2=CC=CC=C2.CCC(=O)OC(CC3=CC=CC=C3)(C(=C)CN(C)C)C4=CC=CC=C4

InChI

InChIKey=LWZYISYGTKMPHQ-KSBRXOFISA-N
InChI=1S/2C22H27NO2.C4H4O4/c2*1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19;5-3(6)1-2-4(7)8/h2*6-15H,2,5,16-17H2,1,3-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1-

HIDE SMILES / InChI
Molecular Formula C22H27NO2
Molecular Weight 337.4553
Charge 0
Count
Stereochemistry UNKNOWN
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )
Molecular Formula C4H4O4
Molecular Weight 116.0722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Dexproxibutene is an experimental agent structurally related to propoxyphene. It is an analgesic agent. Dexproxibutene is not very effective in rheumatoid arthritis pain relief. It is intermediate in effectiveness between distalgesic, codis, aspirin and placebo.

Approval Year

Unknown
149124
Patents

Patents

20100226943
186
6331289
128

Sample Use Guides

In Vivo Use Guide
100 mg (2 tablets) per day
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:39:26 GMT 2025
Edited
by admin
on Mon Mar 31 22:39:26 GMT 2025
Record UNII
KY3JC91C57
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CIBA-44328
Preferred Name English
DEXPROXIBUTENE MALEATE
Common Name English
BENZENEETHANOL, .ALPHA.-(1-((DIMETHYLAMINO)METHYL)ETHENYL)-.ALPHA.-PHENYL-, PROPANOATE (ESTER), (+)-, (2Z)-2-BUTENEDIOATE (2:1) (SALT)
Systematic Name English
BENZENEETHANOL, .ALPHA.-(1-((DIMETHYLAMINO)METHYL)ETHENYL)-.ALPHA.-PHENYL-, PROPANOATE (ESTER), (+)-, (Z)-2-BUTENEDIOATE (2:1) (SALT)
Systematic Name English
DEXPROXIBUTENE HEMIMALEATE
Common Name English
D-1,2-DIPHENYL-2-PROPIONYLOXY-3-(DIMETHYLAMINOMETHYL)-3-BUTENE MALEATE
Systematic Name English
Code System Code Type Description
FDA UNII
KY3JC91C57
Created by admin on Mon Mar 31 22:39:26 GMT 2025 , Edited by admin on Mon Mar 31 22:39:26 GMT 2025
PRIMARY
PUBCHEM
154926050
Created by admin on Mon Mar 31 22:39:26 GMT 2025 , Edited by admin on Mon Mar 31 22:39:26 GMT 2025
PRIMARY
CAS
37554-08-8
Created by admin on Mon Mar 31 22:39:26 GMT 2025 , Edited by admin on Mon Mar 31 22:39:26 GMT 2025
PRIMARY
CAS
54364-09-9
Created by admin on Mon Mar 31 22:39:26 GMT 2025 , Edited by admin on Mon Mar 31 22:39:26 GMT 2025
NON-SPECIFIC STOICHIOMETRY
Related Record Type Details
Structure of DEXPROXIBUTENE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of DEXPROXIBUTENE
ACTIVE MOIETY
NIH
NCATS
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