Colulintide

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:33:14 GMT 2025` Edited by `admin` on `Wed Apr 02 10:33:14 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Origin	SYNTHETIC
Sequence Type	COMPLETE
Record UNII	KX23AY2A39
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Colulintide

Official Name

English

LY-3541105

Preferred Name

English

L-Prolinamide, N-acetyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-seryl-L-threonyl-L-alanyl-L-valyl-L-leucylglycyl-N<sup>6</sup>-[N-(19-carboxy-1-oxononadecyl)-L-?-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-leucy

Systematic Name

English

N-acetyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-seryl-L-threonyl-L-alanyl-L-valyl-L-leucylglycyl-N<sup>6</sup>-[(22S)-22,42-dicarboxy-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23- triazadotetracontan-1-oyl]-L-lysyl-L-leucyl-L-seryl-2-methylalanyl-L-glutamy

Systematic Name

English

colulintide [INN]

Common Name

English

LY3541105

Code

English

Code System Code Type Description

FDA UNII

KX23AY2A39

Created by admin on Wed Apr 02 10:33:14 GMT 2025 , Edited by admin on Wed Apr 02 10:33:14 GMT 2025

PRIMARY

SMS_ID

300000056945

Created by admin on Wed Apr 02 10:33:14 GMT 2025 , Edited by admin on Wed Apr 02 10:33:14 GMT 2025

PRIMARY

INN

13510

Created by admin on Wed Apr 02 10:33:14 GMT 2025 , Edited by admin on Wed Apr 02 10:33:14 GMT 2025

PRIMARY

CAS

2891912-36-8

Created by admin on Wed Apr 02 10:33:14 GMT 2025 , Edited by admin on Wed Apr 02 10:33:14 GMT 2025

PRIMARY

NCI_THESAURUS

C213404

Created by admin on Wed Apr 02 10:33:14 GMT 2025 , Edited by admin on Wed Apr 02 10:33:14 GMT 2025

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Related Record Type Details


					KX23AY2A39

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_14]	SITE_SPECIFIC			.ALPHA.-AMINOISOBUTYRIC ACID	1E7ZW41IQU
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS			N-ACETYLALANINE	26C4VY6Z0M
AMINO_ACID_SUBSTITUTION	[1_11]	SITE_SPECIFIC			N6-(N-(HYDROGEN ICOSANEDIOYL)-.GAMMA.-GLU-BIS(IMINOBIS(ETHYLENOXY)ACETYL))-LYSINE	NVV1P9GCY2

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL