GARETOSMAB

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:57:21 GMT 2025` Edited by `admin` on `Tue Apr 01 21:57:21 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	KR9ZSKO5QE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GARETOSMAB

Official Name

English

REGN-2477

Preferred Name

English

IMMUNOGLOBULIN G4 (234-PROLINE), ANTI-(HUMAN ACTIVIN A) (HUMAN MONOCLONAL REGN2477 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REGN2477 .KAPPA.-CHAIN, DIMER

Systematic Name

English

garetosmab [INN]

Common Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS ACTIVIN A)HUMAN MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-453) (HOMO SAPIENS VH (IGHV4-59*01 (89%) (IGHD)-IGHJ3*02 (93%)) (8.7.20) (1-126)-HOMO SAPIENS IGHG4*01 (HINGE(S10>P(234))) (127-453)) (140-215')-DISULF

Systematic Name

English

GARETOSMAB [USAN]

Common Name

English

GARETOSMAB [JAN]

Common Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS INHBA (INHIBIN SUBUNIT BETA A, ACTIVIN A (INHBA HOMODIMER), ACTIVIN AB (INHBA/INHBB DIMER) AND ACTIVIN AC (INHBA/INHBC DIMER)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-453) (VH (HOMO SAPIENS IGHV4-59*01 (88.7%

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

547016