U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:00:11 GMT 2023
Edited
by admin
on Sat Dec 16 14:00:11 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
KR9ZSKO5QE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GARETOSMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN G4 (234-PROLINE), ANTI-(HUMAN ACTIVIN A) (HUMAN MONOCLONAL REGN2477 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REGN2477 .KAPPA.-CHAIN, DIMER
Systematic Name English
garetosmab [INN]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS ACTIVIN A)HUMAN MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-453) (HOMO SAPIENS VH (IGHV4-59*01 (89%) (IGHD)-IGHJ3*02 (93%)) (8.7.20) (1-126)-HOMO SAPIENS IGHG4*01 (HINGE(S10>P(234))) (127-453)) (140-215')-DISULF
Systematic Name English
GARETOSMAB [USAN]
Common Name English
GARETOSMAB [JAN]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS INHBA (INHIBIN SUBUNIT BETA A, ACTIVIN A (INHBA HOMODIMER), ACTIVIN AB (INHBA/INHBB DIMER) AND ACTIVIN AC (INHBA/INHBC DIMER)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-453) (VH (HOMO SAPIENS IGHV4-59*01 (88.7%
Systematic Name English
REGN-2477
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 547016
Created by admin on Sat Dec 16 14:00:11 GMT 2023 , Edited by admin on Sat Dec 16 14:00:11 GMT 2023
Code System Code Type Description
INN
11041
Created by admin on Sat Dec 16 14:00:11 GMT 2023 , Edited by admin on Sat Dec 16 14:00:11 GMT 2023
PRIMARY
CAS
2097125-54-5
Created by admin on Sat Dec 16 14:00:11 GMT 2023 , Edited by admin on Sat Dec 16 14:00:11 GMT 2023
PRIMARY
USAN
EF-04
Created by admin on Sat Dec 16 14:00:11 GMT 2023 , Edited by admin on Sat Dec 16 14:00:11 GMT 2023
PRIMARY
FDA UNII
KR9ZSKO5QE
Created by admin on Sat Dec 16 14:00:11 GMT 2023 , Edited by admin on Sat Dec 16 14:00:11 GMT 2023
PRIMARY
NCI_THESAURUS
C170022
Created by admin on Sat Dec 16 14:00:11 GMT 2023 , Edited by admin on Sat Dec 16 14:00:11 GMT 2023
PRIMARY
From To
1_22 1_95
2_22 2_95
1_140 3_215
2_140 4_215
1_153 1_209
2_153 2_209
1_267 1_327
2_267 2_327
1_232 2_232
1_235 2_235
2_373 2_431
1_373 1_431
3_23 3_89
4_23 4_89
3_135 3_195
4_135 4_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_303
N 2_303
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL