Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C13H20N2O3S |
Molecular Weight | 284.374 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC(=O)\C=C1/S[C@H](N2CCCCC2)C(=O)N1C
InChI
InChIKey=ZCKKHYXUQFTBIK-XPSMFNQNSA-N
InChI=1S/C13H20N2O3S/c1-3-18-11(16)9-10-14(2)12(17)13(19-10)15-7-5-4-6-8-15/h9,13H,3-8H2,1-2H3/b10-9-/t13-/m0/s1
Molecular Formula | C13H20N2O3S |
Molecular Weight | 284.374 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 1 |
Optical Activity | UNSPECIFIED |
Dexetozoline is a safe and effective diuretic agent in the treatment of acute cardiac failure. In isolated rings of guinea-pig aorta not responding to acetylcholine, the diuretic dexetozoline did not influence basal vascular tone but inhibited noradrenaline- and histamine-induced contractions. Dexetozoline has a very high bioavailability after oral administration and is fairly lipohilic. The half-life of etozolin is 2.5 h. Dexetozoline accumulates in cirrhosis.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1766576
Mean daily dose 666 mg for 7 days
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:33:23 GMT 2023
by
admin
on
Fri Dec 15 16:33:23 GMT 2023
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Record UNII |
KK9WYJ6556
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C270
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admin on Fri Dec 15 16:33:23 GMT 2023 , Edited by admin on Fri Dec 15 16:33:23 GMT 2023
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77519-25-6
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DTXSID601024609
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5093
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SUB07027MIG
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KK9WYJ6556
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637492
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CHEMBL2106290
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76333-71-6
Created by
admin on Fri Dec 15 16:33:23 GMT 2023 , Edited by admin on Fri Dec 15 16:33:23 GMT 2023
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NON-SPECIFIC STEREOCHEMISTRY | |||
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100000083222
Created by
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C78047
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278-423-7
Created by
admin on Fri Dec 15 16:33:23 GMT 2023 , Edited by admin on Fri Dec 15 16:33:23 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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RACEMATE -> ENANTIOMER |
Related Record | Type | Details | ||
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ACTIVE MOIETY |