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Approval Year

2019
334
Substance Class Protein
Created
by admin
on Mon Mar 31 21:28:05 GMT 2025
Edited
by admin
on Mon Mar 31 21:28:05 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type
Sequence Type COMPLETE
Record UNII
KG6VO684Z6
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
POLATUZUMAB VEDOTIN
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
ACD-79B-VCMMAE
Preferred Name English
Polatuzumab vedotin [WHO-DD]
Common Name English
FCU2711
Code English
RO-5541077000
Code English
RO-5541077-000
Code English
RO5541077-000
Code English
ACD79B-VCMMAE
Code English
ACD-79BVCMMAE
Code English
polatuzumab vedotin [INN]
Common Name English
POLATUZUMAB VEDOTIN [MI]
Common Name English
POLATUZUMAB VEDOTIN [USAN]
Common Name English
POLATUZUMAB VEDOTIN [JAN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA AURISTATIN E CONJUGATE, ANTI-(HOMO SAPIENS CD79B (IMMUNOGLOBULIN-ASSOCIATED CD79 BETA)), HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO AURISTATIN E
Common Name English
FCU-2711
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN GENE B29 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MCDS4409A HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MCDS4409A .KAPPA.-CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOH
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
EU-Orphan Drug EU/3/18/2013
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
NCI_THESAURUS C129823
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
FDA ORPHAN DRUG 547416
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C104153
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
USAN
AB-130
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
DRUG BANK
DB12240
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
FDA UNII
KG6VO684Z6
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
MERCK INDEX
m12150
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
WIKIPEDIA
Polatuzumab vedotin
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
ChEMBL
CHEMBL3301582
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
CAS
1313206-42-6
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
EVMPD
SUB177827
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
RXCUI
2174091
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
ALTERNATIVE
DRUG CENTRAL
5333
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
SMS_ID
100000163521
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
DAILYMED
KG6VO684Z6
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
RXCUI
2174090
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
INN
9714
Created by admin on Mon Mar 31 21:28:05 GMT 2025 , Edited by admin on Mon Mar 31 21:28:05 GMT 2025
PRIMARY
From To
1_22 1_96
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_96
2_144 2_200
2_261 2_321
2_367 2_425
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
1_220 3_218
2_220 4_218
1_226 2_226
1_229 2_229
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
Structure of MONOMETHYL AURISTATIN E
TOXIN -> CONJUGATE
POLATUZUMAB VEDOTIN-PIIQ
SUB_CONCEPT->SUBSTANCE
CD79B
TARGET->CONJUGATED TOXIN
Related Record Type Details
POLATUZUMAB VEDOTIN
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUTION [1_220] [1_226] [1_229] [2_220] [2_226] [2_229] [3_218] [4_218] CYSTEINE Amount: Cysteinyl vedotin 6603L01WUR
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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