GLYCLOPYRAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H14ClN3O3S
Molecular Weight	303.765
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCC2

InChI

InChIKey=HNSCCNJWTJUGNQ-UHFFFAOYSA-N

InChI=1S/C11H14ClN3O3S/c12-9-3-5-10(6-4-9)19(17,18)14-11(16)13-15-7-1-2-8-15/h3-6H,1-2,7-8H2,(H2,13,14,16)

HIDE SMILES / InChI

Molecular Formula	C11H14ClN3O3S
Molecular Weight	303.765
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.kyorin-pharm.co.jp/prodinfo/medicine/pdf/DEAMELIN_S_Tablets.pdf
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14570054

Glyclopyramide (N-p-chlorobenzene sul-fonyl, N'-pyrrolidinourea) marketed under the tradename Deamelin-S is a sulfonylurea drug used in the treatment of diabetes mellitus. It has been marketed in Japan.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Type 2 diabetes mellitus 259 Sources: http://www.kyorin-pharm.co.jp/prodinfo/medicine/pdf/DEAMELIN_S_Tablets.pdf	Primary		Approved 8429	DEAMELIN®·S Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

oral use is 125 to 250 mg daily, and as required, may be increased to determine a maintenance dose, with the upper limit of 500 mg daily

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:28:34 GMT 2023` Edited by `admin` on `Sat Dec 16 17:28:34 GMT 2023`
Record UNII	KE474IKG1W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLYCLOPYRAMIDE

Official Name

English

glyclopyramide [INN]

Common Name

English

GLYCLOPYRAMIDE [JAN]

Common Name

English

1-((P-CHLOROPHENYL)SULFONYL)-3-(1-PYRROLIDINYL)UREA

Common Name

English

GLYCLOPYRAMIDE [MART.]

Common Name

English

Glyclopyramide [WHO-DD]

Common Name

English

DEAMELIN-S

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C97936