GLYCLOPYRAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H14ClN3O3S
Molecular Weight	303.765
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCC2

InChI

InChIKey=HNSCCNJWTJUGNQ-UHFFFAOYSA-N

InChI=1S/C11H14ClN3O3S/c12-9-3-5-10(6-4-9)19(17,18)14-11(16)13-15-7-1-2-8-15/h3-6H,1-2,7-8H2,(H2,13,14,16)

HIDE SMILES / InChI

Molecular Formula	C11H14ClN3O3S
Molecular Weight	303.765
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.kyorin-pharm.co.jp/prodinfo/medicine/pdf/DEAMELIN_S_Tablets.pdf
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14570054

Glyclopyramide (N-p-chlorobenzene sul-fonyl, N'-pyrrolidinourea) marketed under the tradename Deamelin-S is a sulfonylurea drug used in the treatment of diabetes mellitus. It has been marketed in Japan.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Type 2 diabetes mellitus 259 Sources: http://www.kyorin-pharm.co.jp/prodinfo/medicine/pdf/DEAMELIN_S_Tablets.pdf	Primary		Approved 8429	DEAMELIN®·S Approved Use Unknown

PubMed

Title	Date	PubMed
[A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus].	2003	14570054

Patents

Sample Use Guides

In Vivo Use Guide

oral use is 125 to 250 mg daily, and as required, may be increased to determine a maintenance dose, with the upper limit of 500 mg daily

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:28:34 UTC 2023` Edited by `admin` on `Sat Dec 16 17:28:34 UTC 2023`
Record UNII	KE474IKG1W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GLYCLOPYRAMIDE

Official Name

English

glyclopyramide [INN]

Common Name

English

GLYCLOPYRAMIDE [JAN]

Common Name

English

1-((P-CHLOROPHENYL)SULFONYL)-3-(1-PYRROLIDINYL)UREA

Common Name

English

GLYCLOPYRAMIDE [MART.]

Common Name

English

Glyclopyramide [WHO-DD]

Common Name

English

DEAMELIN-S

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C97936