OPINIAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H15N3O5
Molecular Weight	329.3074
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(\C=N\NC(=O)C2=CC=NC=C2)C(C(O)=O)=C1OC

InChI

InChIKey=HSYFNANHKYNZNI-GIJQJNRQSA-N

InChI=1S/C16H15N3O5/c1-23-12-4-3-11(13(16(21)22)14(12)24-2)9-18-19-15(20)10-5-7-17-8-6-10/h3-9H,1-2H3,(H,19,20)(H,21,22)/b18-9+

HIDE SMILES / InChI

Molecular Formula	C16H15N3O5
Molecular Weight	329.3074
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13554373 | https://www.ncbi.nlm.nih.gov/pubmed/13289818

OPINIAZIDE (also known as saluzid) was used for the treatment of meningeal tuberculosis in adults and in children. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
[A study of the effect of saluzid on the metabolism of phosphorus compounds in the liver during experimental tuberculosis with the aid of radioactive phosphorus].	1962	13911498
[Saluzid in the treatment of meningeal tuberculosis in children].	1958	13554373
[Saluzid content of biological fluids in meningeal tuberculosis patients; dosage of preparation; clinical and experimental research].	1957	13453403
[Saluzide in the treatment of tuberculous meningitis in adults].	1955-11-01	13289818
[Effects of saluzide treatment on experimental tuberculous meningitis].	1955-11-01	13289821

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:06:26 GMT 2025` Edited by `admin` on `Mon Mar 31 18:06:26 GMT 2025`
Record UNII	KD4681N5W4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OPINIAZIDE

Official Name

English

OPINIAZIDE [MI]

Preferred Name

English

Opiniazide [WHO-DD]

Common Name

English

opiniazide [INN]

Common Name

English

5,6-DIMETHOXYPHTHALALDEHYDIC ACID ISONICOTINOYL HYDRAZONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C280