Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H15ClFN3O2 |
| Molecular Weight | 335.761 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C1=C(C(=O)NC(=O)NC2=CC=C(Cl)C=C2)C(F)=CC=C1
InChI
InChIKey=SRLPZQAEBMZCIJ-UHFFFAOYSA-N
InChI=1S/C16H15ClFN3O2/c1-21(2)13-5-3-4-12(18)14(13)15(22)20-16(23)19-11-8-6-10(17)7-9-11/h3-9H,1-2H3,(H2,19,20,22,23)
| Molecular Formula | C16H15ClFN3O2 |
| Molecular Weight | 335.761 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Clanfenur is a benzoylphenyl urea derivative, developed as an anticancer drug, developed by Solvay. In preclinical studies, clanfenur exhibited anti-tumor activity in mice. A phase I study was initiated to establish the maximum tolerable dose (MTD) and safety of clanfenur. The study had to be discontinued because of intolerance to the vehicle and because the target plasma concentration of 1 ug/mL could not be reached due to very poor solubility of clanfenur.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:05:11 GMT 2023
by
admin
on
Fri Dec 15 16:05:11 GMT 2023
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| Record UNII |
KAM54NKT1Q
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C274
Created by
admin on Fri Dec 15 16:05:11 GMT 2023 , Edited by admin on Fri Dec 15 16:05:11 GMT 2023
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| Code System | Code | Type | Description | ||
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C086806
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SUB06638MIG
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CHEMBL1876799
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68684
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51213-99-1
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DTXSID40965487
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100000084598
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6199
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KAM54NKT1Q
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C78082
Created by
admin on Fri Dec 15 16:05:11 GMT 2023 , Edited by admin on Fri Dec 15 16:05:11 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
