ANTAZONITE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H12N2O2S2
Molecular Weight	268.355
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)\N=C1/SC=CN1CC(O)C2=CC=CS2

InChI

InChIKey=TWOQVRDPCSGVLB-QXMHVHEDSA-N

InChI=1S/C11H12N2O2S2/c1-8(14)12-11-13(4-6-17-11)7-9(15)10-3-2-5-16-10/h2-6,9,15H,7H2,1H3/b12-11-

HIDE SMILES / InChI

Molecular Formula	C11H12N2O2S2
Molecular Weight	268.355
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Description
Sources: DOI: 10.1002/jps.2600551007

Antazonite (R 6438) is an anthelmintic agent. When given orally to chickens in a dose of 160 mg/Kg body weight, all Ascaridia sp., all Hetevakis sp., and about 30% Capillaria sp. are expelled within 48 hr. It is supposed that the anthelmintic activity of Antazonite is due to its major metabolite, R 8141. R 6438 is active as an anthelmintic in poultry, but not in rats. Its metabolite, R 8141, is active in both species.

Approval Year

Sample Use Guides

In Vivo Use Guide

When given orally to chickens in a dose of 160 mg/Kg body weight, all Ascaridia sp., all Heterakis sp., and about 30% Capillaria sp. are expelled within 48 hr.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:58:16 GMT 2025` Edited by `admin` on `Mon Mar 31 17:58:16 GMT 2025`
Record UNII	K9RLQ5L66X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ANTAZONITE

Official Name

English

R 6438

Preferred Name

English

antazonite [INN]

Common Name

English

(±)-N-(3-(2-HYDROXY-2-(2-THIENYL)ETHYL)-4-THIAZOLIN-2-YLIDENE)ACETAMIDE

Systematic Name

English

R-6438

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C250