Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H19N3O2 |
| Molecular Weight | 309.3624 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C=C1)N2N=C3C(=CNC4=C3CCCCC4)C2=O
InChI
InChIKey=XRUUVUYJUULCBQ-UHFFFAOYSA-N
InChI=1S/C18H19N3O2/c1-23-13-9-7-12(8-10-13)21-18(22)15-11-19-16-6-4-2-3-5-14(16)17(15)20-21/h7-11,19H,2-6H2,1H3
| Molecular Formula | C18H19N3O2 |
| Molecular Weight | 309.3624 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/8576841
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/8576841
CGS-20625 is a potent and selective ligand for the central benzodiazepine receptor. It acts as a partial agonist of GABAA channel in vitro and produces anxiolytic and anticonvulsant effects in vivo. The drug has low bioavailability so its clinical applications are limited, and it is mainly used as a tool compound.
Originator
Approval Year
Sample Use Guides
In clinical studies of CGS-20625 pharmacokinetics, the drug was administered orally as a powder (20 mg), as PEG 400 solution or in gelatin capsules.
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:47:33 GMT 2023
by
admin
on
Fri Dec 15 15:47:33 GMT 2023
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| Record UNII |
K9Q4R9S81O
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID30912046
Created by
admin on Fri Dec 15 15:47:33 GMT 2023 , Edited by admin on Fri Dec 15 15:47:33 GMT 2023
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111205-55-1
Created by
admin on Fri Dec 15 15:47:33 GMT 2023 , Edited by admin on Fri Dec 15 15:47:33 GMT 2023
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K9Q4R9S81O
Created by
admin on Fri Dec 15 15:47:33 GMT 2023 , Edited by admin on Fri Dec 15 15:47:33 GMT 2023
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CGS-20625
Created by
admin on Fri Dec 15 15:47:33 GMT 2023 , Edited by admin on Fri Dec 15 15:47:33 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
