ESUPRONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H14O5S
Molecular Weight	282.312
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCS(=O)(=O)OC1=CC2=C(C=C1)C(C)=C(C)C(=O)O2

InChI

InChIKey=CHDGAVDQRSPBTA-UHFFFAOYSA-N

InChI=1S/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C13H14O5S
Molecular Weight	282.312
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800005281 | https://www.ncbi.nlm.nih.gov/pubmed/9174681 | https://www.ncbi.nlm.nih.gov/pubmed/10027835

Esuprone (LU 43839) is a monoamine oxidase type A inhibitor. Esuprone proved to be an effective anticonvulsant in the kindling model. Esuprone was undergoing phase II clinical trials with Knoll (BASF Pharma) in Germany as an antidepressant.

CNS Activity

Originator

Approval Year

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:53:20 GMT 2023` Edited by `admin` on `Sat Dec 16 17:53:20 GMT 2023`
Record UNII	K7EB9E48ZE
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ESUPRONE

Official Name

English

esuprone [INN]

Common Name

English

7-HYDROXY-3,4-DIMETHYLCOUMARIN ETHANESULFONATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C667